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Study Finds First Evidence That Heart Muscles Can Regenerate

By
Andy Corbley
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A left ventricular assist device - credit: HeartWare Inc. / Framingham via AHA open access.
A left ventricular assist device – credit: HeartWare Inc. / Framingham via AHA open access.

A study looking at the bearers of artificial hearts found that a subset of them can regenerate heart muscle tissue—the first time such an observation has ever been made.

It may open the door to new ways to treat and perhaps someday cure heart failure, the deadliest non-communicable disease on Earth. The results were published in the journal Circulation.

A team of physician-scientists at the University of Arizona’s Heart Center in Tucson led a collaboration of international experts to investigate whether heart muscles can regenerate.

According to the Centers for Disease Control and Prevention, heart failure affects nearly 7 million US adults and is responsible for 14% of deaths per year. There is no cure for heart failure, though medications can slow its progression. The only treatment for advanced heart failure, other than a transplant, is a pump replacement through an artificial heart, called a left ventricular assist device, which can help the heart pump blood.

“Skeletal muscle has a significant ability to regenerate after injury. If you’re playing soccer and you tear a muscle, you need to rest it, and it heals,” said Hesham Sadek, director of the University’s Sarver Heart Center.

It was previously thought that when a heart muscle is injured, it could never grow back.

“Irrefutable evidence of heart muscle regeneration has never been shown before in humans,” he said. “This study provided direct evidence.”

The project began with tissue from artificial heart patients provided by colleagues at the University of Utah Health and School of Medicine led by Stavros Drakos, MD, PhD, and a pioneer in left ventricular assist device-mediated recovery.

Teams in Sweden and Germany used their innovative method of carbon dating human heart tissue to track whether these samples contained newly generated cells. The investigators found that patients with artificial hearts regenerated muscle cells at more than six times the rate of healthy hearts.

“This is the strongest evidence we have, so far, that human heart muscle cells can actually regenerate, which really is exciting, because it solidifies the notion that there is an intrinsic capacity of the human heart to regenerate,” Sadek said.

“It also strongly supports the hypothesis that the inability of the heart muscle to ‘rest’ is a major driver of the heart’s lost ability to regenerate shortly after birth. It may be possible to target the molecular pathways involved in cell division to enhance the heart’s ability to regenerate.”

In 2011, Sadek published a paper in Science showing that while heart muscle cells actively divide in utero, they stop dividing shortly after birth to devote their energy to pumping blood through the body nonstop, with no time for breaks.

In 2014, he published evidence of cell division in patients with artificial hearts, hinting that their heart muscle cells might have been regenerating because they were able to rest.

These findings, combined with other research teams’ observations that some artificial heart patients could have their devices removed after experiencing a reversal of symptoms, led him to wonder if the artificial heart provides cardiac muscles the equivalent of bed rest like a person needs when recovering from injury.

ALSO CHECK OUT: Exercise Cuts Heart Disease Risk by 23% With Benefits Doubling for Those With Depression

“The pump pushes blood into the aorta, bypassing the heart,” he said. “The heart is essentially resting.”

Sadek’s previous studies indicated that this rest might be beneficial for the heart muscle cells, but he needed to design an experiment to determine whether patients with artificial hearts were actually regenerating muscles.

Next, Sadek wants to figure out why only about 25% of patients are “responders” to artificial hearts, meaning that their cardiac muscle regenerates.

MORE BREAKTHROUGHS FOR HEART DISEASE: Titanium Maglev Heart Implanted Successfully in a Patient for First Time May Help Others Waiting for a Transplant

“It’s not clear why some patients respond and some don’t, but it’s very clear that the ones who respond have the ability to regenerate heart muscle,” he said. “The exciting part now is to determine how we can make everyone a responder, because if you can, you can essentially cure heart failure.

“The beauty of this is that a mechanical heart is not a therapy we hope to deliver to our patients in the future—these devices are tried and true, and we’ve been using them for years.”

SHARE This First-Ever Demonstration Of Heart Muscle Regeneration With Your Friends… 

“’Tis not enough to help the feeble up, but to support them after.” – William Shakespeare

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Quote of the Day: “’Tis not enough to help the feeble up, but to support them after.” – William Shakespeare

Photo by: Sebastián León Prado

With a new inspirational quote every day, atop the perfect photo—collected and archived on our Quote of the Day page—why not bookmark GNN.org for a daily uplift?

Out-of-Control Invasive Crab Species Has Met its Match: Cute and Hungry Otters

By
Andy Corbley
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An invasive green crab - credit: NOAA Alaska Fisheries
An invasive green crab – credit: NOAA Alaska Fisheries

From California comes the story of native species defending our shores from pillaging green crabs introduced from Europe.

Destroying native crab hatcheries, hunting juvenile salmon, and leveling eelgrass beds, this clawed cancer has met its match in the southern sea otter.

At Elkhorn Slough National Estuarine Research Reserve, a newly invigorated population of otters has shocked scientists by sparing this sensitive ecosystem almost entirely from the crabs’ destruction.

The green crab is one of the most destructive invasive species in US marine territory. They were first introduced to North America in the 1800s, likely hitching a ride in the ballast water of merchant ships from Europe.

Over 1 million green crabs have been caught by Washington wildlife managers following a 2022 emergency order by the state Governor, costing the state $12 million. In California, researchers from the University of California Davis spent years trying to remove them from Stinson Beach’s Seadrift Lagoon, only to see them return. In Oregon, crabbers are encouraged to try and catch at least 35 per trip.

Elkhorn Slough has been occupied by green crabs since the year 2000, but over time, managers noticed something extraordinary. Their numbers were diminishing without any human influence.

Southern sea otters were nearly hunted to extinction in the 19th century for their furs, only gaining a measure of protection in 1913 before an eventual 1977 entry on the Endangered Species List. Lacking the blubber layer of other marine mammals, sea otters need to eat tremendous amounts of calories to stay warm, a voracious appetite which, as it turned out, they trained on the green crabs.

Elkhorn Slough estuary is the only one of its kind in California to have been repopulated by otters. 120 can be found there.

DEFEATING INVADERS: Invasive ‘Murder Hornets’ Are Wiped Out in the US, Using Transmitters That Led Back to the Nests

“The otters eating the crabs benefited the eelgrass, which contributed to better water quality” which helped the otters, said Rikke Jeppesen, an estuarine ecologist with the Elkhorn Slough National Estuarine Research Reserve who was the lead author of a paper published December 10th about the otters and their effects on the ecosystem.

“When the otter population was the lowest back in 2003-2004, we thought the green crabs were going to take over Elkhorn Slough,” she told USA Today. “And then they didn’t. And for that we thank the otters.”

ANOTHER WAY OF DEALING WITH INVASIVES: The Perfect Answer for Berlin’s Invasive Species Problem – Make Them Into Delicious Cuisine

Jeppesen said that she and her colleagues used to be able to catch 100 green crabs in a single trap, whereas today they may not even get 5.

Repopulation of the southern sea otter has been gradual, and despite Elkhorn Slough being the only estuary where they live at maximum capacity, around 3,000 inhabit United States waters. Their recovery should hopefully reverse the decades of destruction wrought by the crabs, and prevent them from recolonizing areas they once conquered.

CELEBRATE These Otters’ Successful Campaign Against The Green Crabs…

Editor’s Note: A previous version of this story described Elkhorn Slough as being located in the Southern United States. This has been corrected.

‘Milking’ the Air for Water: Zero-Energy Technique Doubles Survival Rate for Young Trees to Reforest After Fires

By
Andy Corbley
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The fog catcher's artificial pine needles - credit: LIFE Nieblas
The fog catcher’s artificial pine needles – credit: LIFE Nieblas

In the Canary Islands, in Barcelona, and in Chile, a unique fog catcher design is sustaining dry forests with water without emissions, or even infrastructure.

Replicating how pine needles catch water, the structure need only be brought on-site and set up, without roads, powerlines, or irrigation channels.

Fog catching is an ancient practice—renamed “cloud milking” by an EU-funded ecology project on the Canary Islands known as LIFE Nieblas (nieblas means fog).

“In recent years, the Canaries have undergone a severe process of desertification and we’ve lost a lot of forest through agriculture. And then in 2007 and 2009, as a result of climate change, there were major fires in forested areas that are normally wet,” said Gustavo Viera, the technical director of the publicly-funded project in the Canaries.

The Canaries routinely experience blankets of fog that cloak the islands’ slopes and forests, but strong winds made fog-catching nets an unfeasible solution. In regions such as the Atacama Desert in Chile or the Atlas Mountains of North Africa, erecting nets that capture moisture particles out of passing currents of fog is a traditional practice.

LIFE Nieblas needed a solution that could resist powerful winds, and to that end designed wind chime-like rows of artificial pine needles, which are also great at plucking moisture from the air. However, unlike nets or palms, they efficiently let the wind pass through them.

The water is discharged without any electricity. There are no irrigation channels, and no machinery is needed to transport the structures. The natural course of streams and creeks need not be altered, nor is there a need to drill down to create wells. The solution is completely carbon-free.

WATER IN THE DESERTS: 

In the ravine of Andén in Gran Canaria, a 35.8-hectare (96 acres) mixture of native laurel trees irrigated by the fog catchers enjoys a survival rate of 86%, double the figure of traditional reforestation.

“The Canaries are the perfect laboratory to develop these techniques,” said Vicenç Carabassa, the project’s head scientist, who works for the Center for Ecological Research and Forestry Applications at the University of Barcelona. “But there are other areas where the conditions are optimal and where there is a tradition of water capture from fog, such as Chile and Morocco.”

In Chile’s Coquimbo province, the town of Chungungo is collecting around 250 gallons a day from a combination of locally-made fog catchers at LIFE Nieblas’ pine needle design, the Guardian reports. 

SHARE This Cutting-Edge Fog Catcher Already In Use Around The World… 

Canadians Delighted by Visit from Giant Sea Eagle from the Other Side of the World

By
Andy Corbley
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Steller’s sea eagle – Courtesy of Sandra Moss (Instagram @YQXSandra)
Steller’s sea eagle – Courtesy of Sandra Moss (Instagram @YQXSandra)

Even in the frigid winter temperatures, a national park in Newfoundland was buzzing with visitors who flocked for a chance to see an extremely rare visitor.

Steller’s sea eagle is one of the largest birds of prey on Earth, but is native to Japan, Korea, and Russia. It must have flown thousands of miles to arrive in Newfoundland on its 7.8-foot wingspan.

Steller’s sea eagle – Courtesy of Sandra Moss (Instagram @YQXSandra)

In Terra Nova National Park, Sandra Moss, a photographer who had heard the bird was sighted in the area, brought her camera on a boat trip in Newman Sound. From the gunwales of the boat, she and her husband didn’t see anything, but returning in their car they came across the majestic animal atop a pine tree.

“I can’t explain how exciting it is,” she said in an interview with CBC on Monday. “It’s an incredible feeling to know that that bird has chosen us. That’s what it feels like.”

“I wouldn’t have liked to have a pet or anything in my arms when he was there, he’d probably take you and the pet.”

Despite the extreme vagrancy of this visitor, the eastern seaboard of Canada and even the US have at times seen these birds. On Facebook, members of the Newfoundland and Labrador Birdwatching Group reported last year in nearby Trinity Bay that a Steller’s sea eagle was in the area nesting.

HOW ABOUT THIS FOR A LIFE LIST ENTRY: Mega Rare Blue Rock Thrush Spotted on Oregon Beach Is First Sighting in US History

A year before that, GNN reported that a Steller’s sea eagle was attracting birdwatchers in Boothbay Harbor, Maine five days before Christmas, but that by January 16th it had flown all the way to Denali, Alaska.

NPR at the time reported that the same bird had been seen in various parts of Canada that summer.

MORE RARE SIGHTINGS: Stork That Went Extinct in the UK 600 Years Ago is Spotted in the English Skies: ‘It was a great sign’

Typically 25% larger than a bald eagle, subtlety is not this fish-eater’s specialty, and because their feather markings can be distinct between individuals, they are easy to track.

Terra Nova National Park’s Facebook post on the arrival of the vagrant was full of commenters referencing past sightings, suggesting this year’s visitor is one from previous years.

SHARE This Incredible Sighting With Your Friends… 

Network of AI Monitors Detected 77 Wildfires in California This Year Before a 911 Call Had Been Made for Any

By
Andy Corbley
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Flames from the Bobcat Fire - credit: Eddiem360, CC license, via Wikimedia.
Flames from the Bobcat Fire – credit: Eddiem360, CC license, via Wikimedia.

2024 saw the unparalleled success of an artificial intelligence detection system in California that alerts authorities to the breakout of small wildfires in the state’s dry forests.

A partnership between the California Department of Forestry and Fire Protection (CAL FIRE) and the Univ. of California San Diego called AlertCalifornia has already detected 77 wildfires before a 911 call was made for any of them.

CAL FIRE’s Wildfire AI Detector works alongside UCSD’s AlertCalifornia program to monitor over 1,000 cameras throughout the state with AI to detect wildfires. Governor Newsom’s first budget in 2019 funded 100 of these cameras, and the program has grown ever since.

California has suffered the 8 largest wildfires in the state’s history in just the last 6 years. The interlinked network of cameras, AIs, satellites, and humans is an accommodation a decade in the making.

AlertCalifornia enjoys the support of CA utilities companies, the US Forest Service, the CA Governor’s Office of Emergency Services, and county and tribal governments as well. It’s designed to detect more than just fires, but all natural disasters.

Neal Driscoll, a professor at UCSD’s Scripps Institution of Oceanography, said that the AI system and its algorithms not only need to detect flames, but also smoke and how smoke is moving. It has to detect which direction the fire might move first, and where first responders would be most effective.

GREAT USES FOR AI TODAY: 

Many of the cameras that are now monitored with AI have actually been in place for many years. Governing Magazine reports that these cameras have collected petabytes of image and video data on fires, all of which have been used to train AlertCalifornia’s AI.

“We could go back and say, ‘this is what smoke looks like in this image,’” Driscoll told the Magazine. “We were constantly showing different attributes—smoke columns, smoke being bent over—so we could build up enough high-quality data that the AI could detect change or ignition.”

NASA too, has become involved through its network of satellites. The space agency is also contributing remote-operated drones that can fly at night and dump fire retardants on developing fires whilst first responders are on their way.

“We have to move together, leverage resources, and try to mitigate the impacts of these hazards,” Driscoll said, “because they are only going to get worse.”

SHARE This Great Use Of AI With Your Friends… 

“In planting time learn, in harvest time teach, in winter enjoy.” – William Blake

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Good News Network
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Quote of the Day: “In planting time learn, in harvest time teach, in winter enjoy.” – William Blake

Photo by: Cristina Gottardi

With a new inspirational quote every day, atop the perfect photo—collected and archived on our Quote of the Day page—why not bookmark GNN.org for a daily uplift?

Lowe’s Donates 100 Tiny Homes to Carolina Families Waiting For Rebuilt Housing After Hurricane Flooding

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Good News Network
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Tiny Home donated to NC flood victims by Lowe’s
Tiny Home donated to NC flood victims by Lowe’s

Many families in Western North Carolina were facing the holiday season still in need of the perfect housing, after Hurricane Helene devastated their towns.

But this month, thanks to Lowe’s relief efforts and hundreds of volunteer home builders, dozens of tiny homes were donated to families and installed in time for Christmas Eve.

The tiny homes, which include heat and all the necessities—like a kitchen, bathroom, and two full-size beds—allow families to remain in their neighborhood while their permanent home is rebuilt.

Each home includes fresh seasonal greenery, furnishings, and décor all donated by Lowe’s.

Kathy Graham has lived in the mountains near Asheville for 24 years and when the flood waters receded, there was mold left behind and no heat, but she didn’t want to go anywhere because she couldn’t leave all her animals. That’s why she was overcome with emotion when she saw her new, temporary home for the first time ten days ago.

“Thank God I got my new home—my ‘tiny home’. It’s awesome. It’s gorgeous. I can’t believe it. I can’t even say how much I appreciate it. The Lord has answered my prayers, honestly. Answered my prayers.”

Graham is one of several dozen people who were able to move into the mobile tiny homes in the coming weeks, all thanks to a massive effort that Lowe’s employees and a community of builders have worked round the clock to make happen.

The project came together when Lowe’s Senior Director of Community relations, Julie Yenichek, posed a crazy idea to an old friend, Danny Kelly, the co-owner of Kelly McArdle Construction in Charlotte.

“She told me she wanted to build a hundred tiny homes and I thought, oh my God, that’s perfect. I’ve been looking for my opportunity to do something big, but I don’t have the resources to do it and she said they had all these volunteers lined up, and all the supplies lined up, they just didn’t know how to do it.”

So, a team of volunteers built a prototype in his backyard and soon moved to a Charlotte warehouse and built 16 more with the help of 400 volunteers who signed up to assemble the 8 x16 ft homes right before the holidays.

Lowe’s is purchasing another 50 homes built by Incredible Tiny Homes at its Newport, Tennessee facility—67 units to give families who need a home for the holidays, with an additional 33 delivered by early January. Watch one of the heartwarming deliveries below…

 

Amanda Hayes and Randy Jones, co-owners of Incredible Tiny Homes, said they watched as the floods ravaged their East Tennessee hometown. They were thrilled when Lowe’s called them with a solution for families—funding the construction of many more of their tiny homes to be driven to sites all over.

“The first home went to a mom with three kids and it really hit me whenever they sent me the pictures… it was like, my goodness, these people don’t want to leave their land,” said Amanda.

Photos by Lowe’s

“It just means everything. To provide housing for these people who have lost everything, this is the most special thing that we’ve ever done with Lowe’s.”

Permanently fixed on wheels, they can sleep three to four people, and can connect to electricity.

The Home Builders Association of Greater Charlotte is spearheading the volunteer effort. Jennifer Schuster, their Executive Officer, says they had more than 400 volunteers sign up to help put the tiny homes together in just a matter of seven days.

“We’ve had volunteers—everything from framing crew, roofing crew, plumbers, electricians, to the actual builders in the markets—sending their project managers to our associates, which are the suppliers, sending their people to be a part of this.”

AMAZING: Thousands of Circular Homes Are Surviving Hurricanes Across the US Thanks to North Carolina Company

Yenichek says the goal is to get at least 100 tiny homes completed and delivered to the flood victims in the mountains as soon as possible, as part of Lowe’s $12 million pledge to support recovery efforts.

The US disaster agency FEMA has approved $279 million, which includes funds for renting a home or apartment for over 140,000 households, according to local WLOS-TV News, but some people don’t want to leave their communities, so have been in FEMA paid hotel rooms or makeshift tents or sheds.

The effort is also supported by Habitat for Humanity, NASCAR haulers—who towed the homes to towns across the region—BeLoved Asheville, the Appalachia Service Project, and SunCap Property Group which donated the warehouse space to host the build.

CHECK OUT: 14 Luxury Hotels Are Donating Outdated Furniture to Low-Income Families in Need

WARM PEOPLES’ HEARTS By Sharing This Good News On Social Media…

Neglected Beagle Freed From 4ft Chain Enjoys First Cozy Christmas Thanks to Anonymous Caller

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Newlyweds Dan and Katherine with Cooper – PETA
Newlyweds Dan and Katherine with Cooper – PETA

A beagle mix named Copper celebrated his first Christmas safe and warm indoors with a loving family after being rescued from the end of a chain, where he lived neglected every day exposed to the elements without shelter.

The eight-year-old dog looked emaciated, and there was no water bowl, when rescuers approached him. They later discovered he was also plagued with parasites.

It all started with a winter phone call from an anonymous tipster who alerted the Twin County Humane Society in Galax, Virginia, saying there was a very thin dog tied up outside that may be in need of help.

The humane society asked two PETA fieldworkers—who were in town for an event that sterilized 229 cats and dogs for free—to investigate. A local animal control officer joined Adam and Jenny on the scene and discovered that Copper was kept unattended outside on a tether that allowed only 4 feet of movement with no doghouse or shelter.

Despite the neglect, from the moment the PETA coworkers met him, Copper was amazingly sweet-natured. After the dog’s owner understood that she could face a criminal charge of cruelty-to-animals, she signed over ownership of the pup.

They immediately secured veterinary care and the sweet animal was adopted by PETA staffers Katherine Sullivan and Dan Paden, who were newlyweds planning their first holiday together. (See the heartwarming video at the bottom…)

“Copper’s recovery and his happy new life are all thanks to one good Samaritan: a mystery caller I will forever think of as my sweet beagle’s ‘Secret Santa’,” wrote Katherine in a blog post.

Like an old penny that just needed polishing, all this copper-hued senior beagle needed was a little TLC – PETA

With his bodyweight nearly doubled and his spirit fully renewed, for the first time in his life Copper’s Christmas season included strolls through dog-friendly parks, plenty of healthy treats under the tree—and best of all, a family that loves and protects him.

CHECK OUT: Saddest Dog in Town Spent Over 2 Years at a Shelter But Finally Gets a Home for Christmas

“The weather outside might be frightful, but inside it’s so delightful for Copper (at last), all thanks to one caring person who spoke up when they saw an animal in need,” said PETA Senior Vice President Daphna Nachminovitch.

Copper not only loves other dogs, but cats, too, which proved perfect for Dan and Katherine’s family, which includes three rescued cats in a home where he will enjoy the rest of his golden years.

Watch the heartwarming happy ending…

SHARE THE TRANSFORMATION With Dog Lovers On Social Media… 

Best Holiday Light Show in the Sky Wins Guinness World Record With Dazzling 5,000 Drone Christmas Display–LOOK

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5000 drones form Santa Claus in the night sky over Mansfield, Texas – Courtesy Sky Elements
5000 drones form Santa Claus in the night sky over Mansfield, Texas – Courtesy Sky Elements

To celebrate the holiday season, Sky Elements provided some happy drone news by creating the largest swarming light show ever to have flown in the United States.

Set to music, the light show created massive motion-filled scenes that captured the spirit of the holidays—a Thanksgiving turkey, a winter wonderland scene, a gingerbread village, and, of course, Santa’s sleigh with reindeer.

Making the holiday a little more magical in Mansfield, Texas, 4,981 drones lit up the sky to ring in the season.

Partnering with UVify, a manufacturer of swarm drones for light shows, the team
began the show with a lifelike turkey, full of movement and color, spreading wide its tail feathers. (See the video at the bottom…)

Thanksgiving turkey drone show – Courtesy Sky Elements

A wintery wonderland appeared next, centered around a massive snowman. A surreal gingerbread village also was featured, with candy cane street lamps and gumdrop rooftops. The sun sets on the cozy winter village as lights illuminate the homes and smoke billows out of the chimneys.

For the finale, Santa Claus in his sleigh with two reindeer, waved at the audience.

“We teamed up to create holiday cheer in a new, fun way: by making the largest gingerbread village… made entirely of drones,” said Preston Ward, Chief Pilot of Sky Elements.

“Not only did we spread the holiday spirit, but we also scored our 11th Guinness World Record.”

Flying the nearly 5,000 drones in formation was quite a feat for the private company, and it took 40 people to coordinate the exhibition.

Thousands of drones lift-off for light show in Mansfield, Texas, with crew looking on – Courtesy Sky Elements

“Shout out to our unforgettable pilots, crew leads, animators, and drone crew that made this all possible.”

Watch the awesome show below…

ALSO CHECK OUT: Using Drone, She’s Tracked Down and Reunited 330 Lost Dogs with Owners for Free – Using Thermal Imaging

SPREAD SOME CHEER By Posting These Delightful Drones On Social Media…

Key Alzheimer’s Breakthrough Identifies Stress-Related Cellular Mechanism Driving the Disease

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Alzheimer’s brain study highlights microglia – by Pinar Ayata / CUNY

Scientists investigating Alzheimer’s disease have made a key breakthrough, identifying a vital cellular mechanism driving the most common cause of dementia.

The research from the City University of New York (CUNY) provides a promising target for drug therapies that could slow, and possibly reverse, the disease’s development.

The study, published in the journal Neuron, highlights microglia—the brain’s primary immune cells—and their critical link to cellular stress in the brain—both the protective and harmful responses associated with Alzheimer’s.

Microglia, often dubbed the brain’s first responders, are now recognized as a significant causal cell type in Alzheimer’s pathology. However, these cells play a double-edged role: some protect brain health, while others worsen neuro-degeneration.

“We set out to answer what are the harmful microglia in Alzheimer’s disease and how can we therapeutically target them,” said Pinar Ayata, the study’s principal investigator and a professor with CUNY’s neuroscience initiative within its Advanced Science Research Center.

His team pinpointed a “novel neurodegenerative microglia phenotype” in Alzheimer’s disease characterized by a stress-related signaling pathway.

Activation of this stress pathway, known as the integrated stress response (ISR), prompts microglia to produce and release toxic lipids. These lipids damage neurons and oligodendrocyte progenitor cells—two cell types essential for brain function and most impacted in Alzheimer’s disease.

Blocking this stress response or the lipid synthesis pathway reversed symptoms of Alzheimer’s disease in preclinical models.

Alzheimer’s brain study highlights role of stress in microglia – by Pinar Ayata / CUNY

DEMENTIA PREVENTION: High Levels of Physical Fitness Linked to Lower Dementia Risk in Those with Genetic Predisposition

Using electron microscopy, the research team identified an accumulation of “dark microglia”, a subset of microglia associated with cellular stress and neuro-degeneration, in postmortem brain tissues from Alzheimer’s patients.

The cells were present at twice the levels seen in healthy-aged people.

“These findings reveal a critical link between cellular stress and the neurotoxic effects of microglia in Alzheimer’s disease,” said study co-lead author Anna Flury.

Ms. Flury, a member of Prof. Ayata’s lab and a Ph.D. student, says, “Targeting this pathway may open up new avenues for treatment by either halting the toxic lipid production or preventing the activation of harmful microglial phenotypes.”

The team’s study highlights the potential of developing drugs that target specific microglial populations or their stress-induced mechanisms.

STRESS REDUCTION IN BRAIN? Study Links Recreational Cannabis Use to Lower Risk of Cognitive Decline and Dementia-Related Diseases

“Such treatments could significantly slow or even reverse the progression of Alzheimer’s disease, offering hope to millions of patients and their families,” concluded co-lead author Leen Aljayousi, a member of Prof Ayata’s lab.

SHARE THE HOPE By Posting The Team’s Findings On Social Media…

“That is the function of us all, as creative artists: to make the truth irresistible.” – Audre Lorde

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Quote of the Day: “That is the function of us all, as creative artists: to make the truth irresistible.” – Audre Lorde 

Photo by: Jr Korpa

With a new inspirational quote every day, atop the perfect photo—collected and archived on our Quote of the Day page—why not bookmark GNN.org for a daily uplift?

Owl Flies Down Chimney And Perches on Top of Family’s Christmas Tree (WATCH)

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Barred owl on Burgoyne family Christmas tree – Courtesy of Savannah Burgoyne / Animal Welfare League of Arlington
Barred owl on Burgoyne family Christmas tree – Courtesy of Savannah Burgoyne / Animal Welfare League of Arlington

Twas the week before Christmas, and perched on the tree was an magical visitor as wise as can be…

It came down the chimney, but wasn’t named Santa, a majestic barred owl dropped in unexpected.

Savannah Burgoyne was at home with her young children in Arlington, Virginia, when she first saw the bird fly through her living room and land atop the tree—and a finer tree topper you’ll never find.

She called the Animal Welfare League of Arlington, and Spencer Murray was dispatched on the jolly house call.

His strategy was to let the bird tire itself out flying from the tree to the kitchen cabinets, with a large net ready to scoop the predator out the double french doors, and back into the suburban skies.

Murray took to social media to post photos and remind everyone to keep their chimneys capped with wire to prevent curious critters from coming inside.

Savannah joked that she was disappointed there was no letter from Hogwarts that came with the owl.

Choosing that local Welfare League, which shelters homeless animals and facilitates adoptions, probably was not the correct call to make, nor would a local animal control agency.

Instead, in a situation like this, homeowners should call a local wildlife rescuer, which is better prepared to respond, although Murray reported the owl was safely captured and led outside. (See for yourself in the video below.)

On the bright side, the group did send the family a surprise holiday gift: an owl tree-topper to remember their encounter forever, and to replace the star that collapsed under the weight of the beefy holiday visitor.

ALSO ADORABLE: Australian Woman Finds Koala Hanging Out in Her Christmas Tree – And the Photos are Adorable

We like to think the Burgoyne family also has a stellar Christmas card idea for next year.

DON’T FORGET TO SHARE This Owl-some Video With Bird-Lovers on Social Media…

Insurer Denies Prosthetic So Family Crowdfunds $30k–But Angel Steps In and Girl Gives Money to Boy Who Needs One

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Remi Bateman and Taj Johnson Jr. getting bionic Hero Arms – via SWNS
Remi Bateman and Taj Johnson Jr. getting bionic Hero Arms – via SWNS

The family of a 9-year-old who was born without a left hand raised the $24,000 needed for a new prosthetic arm, after the cost was denied by their insurance company—but now the girl is paying it forward to another child, after a Good Samaritan stepped in to cover the full cost of hers.

Remi Bateman, who outgrew her conventional prosthetic, got the chance to try out a robotic ‘Hero Arm’ made by Open Bionics—and she loved it.

But the family in Utah was left devastated when insurer Select Health deemed the prosthetic “not medically necessary”, which was surprising, since they’d approved three prosthetics before in her lifetime. Even after two different appeals, the company said the high-tech device was for “cosmetic use only”, which left Remi in tears.

So the family launched a GoFundMe campaign and was able to quickly raise the $24,000 to buy the Hero Arm outright—but then a company called CrowdHealth stepped in to pay for her arm in full.

Andy Schoonover, the CEO of the insurance alternative that helps people negotiate lower costs for medical bills, was looking for a way to give back over the holidays. He called the family on Dec. 16 after seeing the story about their fundraiser on social media.

He encouraged Remi to use the GoFundMe donations however she wished, and the little girl knew immediately what she wanted to do—she wanted to help another child buy a Hero Arm.

The Batemans found the fundraising page for Taj Johnson Jr. from Virginia, also born without a left arm, who was raising money for a bionic limb.

She gave the 9-year-old the money so now both kids will get to do what their peers can do, like tying a shoe or hanging on the monkey bars on a playground—thanks to the device controlled via sensors atop their forearm muscles.

9-year-old Remi Bateman using a fork with a bionic ‘Hero Arm’ – via SWNS

“I’m so excited to get my Hero Arm, I could jump to the moon,” said Remi, who ordered her multi-grip bionic hand in the color pink.

“Being able to help Taj means a lot to me.”

Taj’s mom was shocked and ecstatic.

“We are just so grateful to Remi and her family,” said Kaitlin Skinner, who had only managed to raise $1,500 on their GoFundMe page. “This is a blessing.”

Remi’s mom, Jami, especially enjoyed telling Taj’s family. “They were so surprised and grateful to receive the help.

“Remi absolutely needs this device to aid her in two-handed tasks and activities. It is going to support her spinal and shoulder health as she grows too.”

ALSO CHECK OUT: Three Children Receive ‘the Best Christmas Present Ever’ – Bionic Arms

Bionic Hero Arm –Credit: Open Bionics

“We are thrilled that CrowdHealth stepped forward to pay for Remi’s arm, enabling us to use the donations to help another limb-different family in need.”

Remi’s quality of life is about to change for the better, as Open Bionics, based in the UK, says they should be ready to fit her pink arm in January.

AMAZING: The Humble Shoe Shiner Who Used All $200,000 of His Tips to Help Uninsured Children

The family, having tasted the sweetness of philanthropy, decided to keep their GoFundMe page open to collect more funds, working towards the goal to help another child named Faith to get a Hero Arm.

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Englishwoman Wakes Up From Stroke Speaking Italian With an Accent–And She’s Never Even Been to the Country

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Good News Network
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Althia Bryden in 2024 – SWNS
Althia Bryden in 2024 – SWNS

A stroke has left a British woman with an Italian accent and an ability to speak the language, despite never having visited the country.

Althia Bryden’s husband found her unresponsive one evening this summer and unable to talk, so immediately called an ambulance. The 58-year-old stayed in the hospital for nine days after doctors discovered she had suffered a stroke caused by a carotid web, which can interrupt the blood flow to the brain.

After a surgery to remove it—and after three months of being unable to talk—she woke up with an Italian accent and the ability to use rudimentary words in the language.

“I spent three months after my stroke thinking I’d never be able to talk again,” the grandmother from North London told SWNS news. “I felt like a shell of the person I once was.”

“After my carotid web surgery, a nurse came to my hospital bed to do a routine check, and completely out of the blue, I just started speaking. She looked as shocked as I did.

“I remember thinking ‘who is that talking?’.

“Firstly, I couldn’t believe it was me talking, but I also didn’t recognize the sound of my voice.”

Doctors began gathering around Althia’s bedside to hear her talk.

“The more I spoke, the more confused we all became.

“It was clear that I did have a strong Italian accent, and I had no control over the sound I was making when talking.”

To her amazement, she was also able to speak Italian—a language she says she never learned or spoke before.

“Without realizing, I will say an Italian word mid-conversation, which is the Italian word for what I’m trying to say in English. I have no idea I’m about to do it, my brain just converts the English word into Italian.”

Doctors diagnosed Althia with ‘Foreign Accent Syndrome’, a rare medical condition that causes a person’s speech to sound like they have a foreign accent, even though they haven’t acquired it.

The term was first coined in 1982 by H.A. Whitaker, who explained that the condition is “clearly related to central nervous system damage”. While rare, well over 100 cases have been reported in the medical literature.

Given the rare nature of the disorder, Althia has struggled because there is nobody she can relate to.

“Doctors and nurses see me as a bit of a medical marvel; none of the therapists or medical staff has dealt with Foreign Accent Syndrome (also known as FAS) in their whole careers.

“I’m so grateful to be alive after my stroke, and to be able to communicate after living with no speech for three months, but living with FAS is really hard.”

INTERESTING WORDS: 30-50% of Twins Develop a Language Exclusive to Them During Childhood

“I wake up most mornings hoping that my old voice will be back again. I don’t feel like me with this foreign accent. I can even hear the accent in my head when I’m thinking. It’s such a very strange feeling.

“I try my hardest to stay positive and upbeat (and) I remind myself that I’m still here today, and have my husband, two sons, and their beautiful families with me.”

FUN FOR FANS: Duolingo Has Created a Course for “High Valyrian” the Dragon Language From Game of Thrones

With the support from the Stroke Association and their support groups, she has met many other stroke survivors locally.

“It’s so helpful to share our lived experiences. As much as every stroke is different, there is always something that two stroke survivors can bond over.

But she has yet to meet anyone who has Foreign Accent Syndrome—and she wishes she could bid ‘Arrivederci’ to the accent.

SHARE THE AWE-INSPIRING STORY With Language Lovers on Social Media…

Your New Horoscope For 2025 – ‘Free Will Astrology’ by Rob Brezsny

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Good News Network
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Our partner Rob Brezsny, who has a new book out, Astrology Is Real: Revelations from My Life as an Oracle, provides his weekly wisdom to enlighten our thinking and motivate our mood. Rob’s Free Will Astrology, is a syndicated weekly column appearing in over a hundred publications. He is also the author of Pronoia Is the Antidote for Paranoia: How All of Creation Is Conspiring To Shower You with Blessings. (A free preview of the book is available here.)

Here is your weekly horoscope…

FREE WILL ASTROLOGY – Week of December 28, 2024
Copyright by Rob Brezsny, FreeWillAstrology.com

CAPRICORN (Dec. 22-Jan. 19):
Since 1985, musician David Gilmour has led Pink Floyd. The band has sold over 250 million records. He’s in the Rock and Roll Hall of Fame in both the UK and the US. But my favorite thing about Gilmour is that he’s a passionate activist who has crusaded for environmentalism, poverty, and human (and animal) rights. A few years ago, he auctioned off 120 of his guitars, raising over $21 million for an environmentalist charity. In accordance with astrological omens, I propose we make him one of your inspirational role models in 2025, Capricorn. May he mobilize you to use your stature and clout to perform an array of good works that are of service to your world.

AQUARIUS (Jan. 20-Feb. 18):
Aquarian author Virginia Woolf extolled the virtues of cultivating a supple soul that thrives on change. She pledged to be relentless in her commitment to be authentically herself and not succumb to groupthink. I recommend you make these two of your featured themes in 2025. To inspire your efforts, I will quote her radical perspective at length: “Movement and change are the essence of our being; rigidity is death; conformity is death: let us say what comes into our heads, repeat ourselves, contradict ourselves, fling out the wildest nonsense, and follow the most fantastic fancies without caring what the world does or thinks or says.”

PISCES (Feb. 19-March 20):
In 1992, two friends promised each other that if either of them ever won the lottery, they would share it with the other. 28 years later, that’s exactly what happened. In 2020, Thomas Cook bought a ticket that turned out to be the winner of the Powerhouse jackpot in Wisconsin. He called Joseph Feeney with the good news. After paying taxes, both men were $5.7 million richer. I am not predicting the exact same sequence for your future, Pisces. But like Cook and Feeney, I expect you will glean pleasing rewards generated from seeds planted in the past.

ARIES (March 21-April 19):
In 2025, I would love for you to specialize in making new connections and deepening your existing connections. I hope you will summon extra creativity and panache as you regularly blend your beautiful energies with others’ beautiful energies. I predict you will thrive on linking elements that should be linked but have never been before. What do you think, Aries? Does it sound fun to become a playful master of mixing and combining? Would you enjoy generating splashy unifications that serve your dreams?

TAURUS (April 20-May 20):
“Confidence is 10 percent hard work and 90 percent delusion,” declared Taurus comedian Tina Fey. But I believe you will disprove that assessment in the coming months. The work you do will be unusually replete with grace and dynamism. It will be focused and diligent work, yes, but more importantly, it will be smart work that’s largely free of delusion. That’s why I’m inclined to revise Fey’s formula for your sake. In 2025, your brimming levels of confidence will be primarily due to your fine, conscientious, effective work.

GEMINI (May 21-June 20):
In the 1960s, a Swedish journalist tried an experiment. He wanted to see if art critics could distinguish between abstract paintings made by skilled artists and those created by a four-year-old chimpanzee whose pseudonym was Pierre Brassau. Surprise! Many of the critics treated all the paintings with equal respect. One even gave special praise to Pierre Brassau, describing his strokes of color as having “the delicacy of a ballet dancer.” I’m authorizing you to unleash your inner Pierre Brassau in the coming months, Gemini. Be an innocent rookie, a newcomer with great instincts, an exuberant amateur who specializes in fun experiments. Do you know what beginner’s mind is? You approach every experience with zero assumptions or expectations, as if you were seeing everything for the first time.

CANCER (June 21-July 22):
Ohio’s Cuyahoga River used to catch on fire regularly. The cause was pollution. For a hundred years, industries had poured their wastes into the waterway. The surface was often dotted with oil slicks. But after a notorious river fire in 1969, the locals decided to remedy the situation, aided by the newly established Environmental Protection Agency. Today, the Cuyahoga still isn’t 100% clean, but it’s far better. It hosts kayaking, fishing, and paddle boarding. I propose we use its rehabilitation as a symbol for you in 2025. You will have welcome opportunities to clean up messes that have lingered for far too long. Please take full advantage of these cosmic invitations to sweep karmic debris out of your life.

LEO (July 23-Aug. 22):
Steve Jobs, founder of Apple computers, said, “The people who are crazy enough to think they can change the world are the ones who do.” I propose that you make this one of your mottoes in 2025. More than ever before, you will have exceptional power to transform the environments you share with others. You will have an enhanced ability to revise and reinvigorate the systems and the rules you use. Don’t underestimate your influence during the coming months, Leo. Assume that people will be listening especially closely to your ideas and extra receptive to be affected by you.

VIRGO (Aug. 23-Sept. 22):
I will give you four related terms to describe your key motif in 2025: 1. Your Soul’s Code. 2. Your Master Plan. 3. Your Destiny’s Blueprint. 4. Your Mission Statement. All four are rooted in this epic question: What is your overarching purpose here on earth, and how are you fulfilling it? The coming months will be a time when you can make dramatic progress in formulating vivid, detailed visions of the life you want to live. You can also undertake robust action steps to make those visions more of a practical reality. I encourage you to write your big-picture, long-range dreams in a special notebook or a file on your tech device. Keep adding to the text throughout the coming months.

LIBRA (Sept. 23-Oct. 22):
People in India were the first to discover diamonds buried in the earth. Most historians believe it happened in the 4th century BCE. For the next two millennia, India remained the only source of diamonds. Finally, new stashes were found in Brazil in 1725 and in South Africa in the 1870s. Let’s use this 2,000-year gap as a metaphor for your life. I suspect that far too many months have passed since you have located a fresh source of a certain treasure or bounty you crave. That will change in 2025. Here come long-delayed blessings!

SCORPIO (Oct. 23-Nov. 21):
In my vision of your life in 2025, you will dramatically enhance how togetherness works for you. Below are four questions to help guide your explorations and breakthroughs. 1. Is it feasible to change yourself in ways that enable you to have a more satisfying relationship with romantic love? 2. Will you include your intimate relationships as an essential part of your spiritual path—and vice versa? 3. What work on yourself can you do to heal your old wounds and thereby make yourself a better partner and collaborator? 4. Can you help your best allies to heal their wounds and thereby become better partners and collaborators?

SAGITTARIUS (Nov. 22-Dec. 21):
In Japanese, the word for “frog” sounds similar to the word meaning “to return.” That’s one reason frogs have been lucky in some circles of Japanese culture. They symbolize the blessing that occurs when travelers return home safely, or when health is restored, or when spent money is replenished. I bring this to your attention, Sagittarius, because I suspect 2025 will be a time when satisfying and enjoyable returns will be a key theme. Consider keeping the likeness of a lovable frog in your living space.

WANT MORE? Listen to Rob’s EXPANDED AUDIO HOROSCOPES, 4-5 minute meditations on the current state of your destiny — or subscribe to his unique daily text message service at: RealAstrology.com

(Zodiac images by Numerologysign.com, CC license)

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“Movement and change are the essence of our being; rigidity is like death.” – Virginia Woolf 

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Good News Network
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Getty Images for Unsplash+

Quote of the Day: “Movement and change are the essence of our being; rigidity is death.” – Virginia Woolf 

Photo by: Getty Images for Unsplash+

With a new inspirational quote every day, atop the perfect photo—collected and archived on our Quote of the Day page—why not bookmark GNN.org for a daily uplift?

Getty Images for Unsplash+

Cotton and Squid-Bone Sponge Can Soak Up 99.9% of Microplastics, Scientists Say

By
Andy Corbley
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Photo by Anastasiia Nelen on Unsplash
Photo by Anastasiia Nelen on Unsplash

A matrix of squid bone and cotton cellulose offers a low-cost, scalable solution to global microplastic poisoning according to a new study from China.

Attempting to find a material that would address all common concerns with microplastic filtration, the scientists’ cotton-squid sponge displayed 99.9% efficacy and a “remarkable reusability.”

Tested in water found in a lake, a scummy pond, the sea, and an irrigation ditch, the 99.9% removal rate fell only a few percentage points after several decontamination cycles, the authors report in Science Advances.

It is becoming increasingly clear that microplastic contamination has the potential to surpass all other health and environmental concerns as more discoveries about the adverse effects of common microplastics are made.

Consequences like increased cancer risk, hormonal dysregulation, and developmental delays are better understood, but recent research has also linked it to a two-fold increase in the risk of heart attack or stroke if the particles are embedded in heart tissue.

Along with their ubiquity (microplastics have been found in every environment on Earth, from the jetstream to the depths of the ocean) the term “microplastics” can refer to as many as 16,000 different chemicals, of which some may be more toxic than others, or be harder to remove from the body.

This is especially true for a class of chemicals known as PFAS—polyfluoroalkyl substances—often called “forever chemicals” for their durability in the natural environment compared to other plastics. That durability is replicated inside the human organism, with natural detox systems like urination and perspiration unable to completely cleanse the tissues from PFAS once ingested.

OTHER SOLUTIONS TO MICROPLASTICS: 

The sponge is made from cotton and chitin found in the bone tissues of a squid. It was manufactured with existing machines like mechanical stirrers and freeze dryers to ensure it would be as cheap and scalable as possible.

The authors from the University of Wuhan in China note that many microplastic filters and sponges have achieved between 95 and 99% purities in experimental settings, but haven’t been used in the real world because the materials and manufacturing methods are too expensive, too complex, or produce too little filtration material.

From the offset by contrast, the team from Wuhan tried to make it from materials that could be acquired all around the world for pennies, and with machines that would be available to any manufacturer, even those in developing nations.

With proper testing at a commercial or industrial scale, they estimate the sponges could become household and municipal products within a couple of years.

Saying ‘if there’s a will there’s a way’ to solve the microplastic pollution pandemic isn’t quite accurate because there are already several ways. It remains only to separate out the great ways from the good ways and implement them as fast as possible.

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Special Holiday Delivery From the Middle East—The Stray Cat who Stole a Sergeant’s Heart is Now Rescued

By
Andy Corbley
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Air Force Technical Sergeant Tracy with Walter
Air Force Technical Sergeant Tracy with Walter

A deployed US airwoman had her Christmas wish fulfilled thanks to a nonprofit that undertook a special holiday delivery—rescuing the stray cat who stole her heart.

US Air Force Technical Sergeant Tracy was stationed in the Middle East when she found a kitten on her base and named it Walter.

The orange tabby offered comfort to the woman so far from home, but as the end of her deployment neared, she couldn’t bear to leave him behind knowing he risked starvation or euthanasia.

So she turned to the veteran-led, New York-based Paws of War to help. They focus on entering countries where US soldiers are deployed and rescuing animals they may have formed bonds with.

The CBS News station in New York reported that it can cost as much as $10,000 to perform these extractions, as they require plane tickets, various medical procedures, and paperwork filings with governments at home and abroad.

But Walter was rescued in time for Christmas, when, after arriving first in New York, Paws of War volunteer and US Army veteran Dereck Cartwright drove the orange tabby to the waiting arms of Sgt. Tracey’s husband all the way in New Hampshire.

SIMILAR STORIES LIKE THIS:

“[It’s] the least we can do for these service members who are sacrificing so much, not only their safety—they are going to be away from their families this holiday, they are in a faraway place, a dangerous place,” said Robert Misseri from Paws of War.

WATCH the story below from CBS 2 New York…

SHARE This Sweet Homecoming For A US Veteran’s Cat At Christmas Time…

Barstool Sports’ Dave Portnoy Channels Thousands in Donations to Save Baltimore Pizzeria

By
Andy Corbley
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- credit: @stoolpresidente via X, screengrab
– credit: @stoolpresidente via X, screengrab

Down on Light St. in Baltimore, a little pizzeria set to shutter by Christmas has received a huge helping hand—a Christmas miracle, one might say.

Each box of pie came with a note saying that unless Little Brick Over Pizzeria received a serious amount of business or donations, it would close on December 25th.

Enter Barstool Sports’ Dave Portnoy for one of his famous One Bite pizza reviews.

Giving it a “solid 7.9” and describing it as a kind of “thin New York style” his review and publicity means that now, the oven at Tiny Brick Oven is overflowing with pies to satisfy a line out of the door.

Owner Will Fagg, described by one part-time employee as her “guardian angel,” was a big fan and follower of Portnoy, who had followed his work during the COVID-19 lockdowns helping small hospitality businesses stay open.

When Portnoy asked how things were going at Little Brick Oven, he was shocked to hear the prognosis was grim. Owner Will would later tell WJZ 13 News that the problem is the money it costs to get a liquor license, something which the new market across the street has, and which is driving him out of business.

Getting his pie, Portnoy, who had by then heard the whole predicament, insisted on paying for it, joking “you can’t tell me you’ve got no money and then not ask me to pay for it.”

– credit @stoolpresidente via X, screengrab
– credit @stoolpresidente via X, screengrab

After his first bites, Portnoy shows the camera the appeal for financial assistance from Fagg, who’s also a veteran, on the box and says succinctly “there’s no way this place should be goin’ out of business.”

OTHER CROWNFUNDING KINGS: YouTuber ‘MrBeast’ Just Removed 17,000 Tons of Ocean Trash by Harnessing Social Media Influencers and Fans

Calling Fagg the nicest guy you could hope to meet, Portnoy goes back in to ask how much money Fagg would need to keep the place open for a year, to which the owner replies $60,000 for costs and the liquor license.

– credit @stoolpresidente via X, screengrab

“Done” replies Portnoy.

The review went viral, wracking up 14 million views on X alone; and on Christmas Eve, Tiny Brick Oven had a line out the door and phones ringing non-stop.

“We’ve never had a line like this. We’ve never had a line like this,” Fagg told the KXII news cameras from behind his counter, where he stood in his red chef’s coat and hat rolling dough and splattering sauce.

YOU MAY ALSO LIKE: United Pilot Orders 30 Pizzas to Feed Passengers After Emergency Landing for Medical Care

The donations poured as Christmas Eve became Christmas Day.

“It’s an incredible feeling. I’ve always had a lot of community support. It’s overwhelming, and I really thank everybody so much,” Fagg said.

WATCH the story below from WJZ 13 News…

SHARE Portnoy’s Good Deed, This Good Slice, And A Man’s Livelihood Saved…

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