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Dramatic Reduction in Teen Suicide Attempts After Same-sex Marriage Legalization

Pride Flag-CC Get Event Photos

The implementation of state laws legalizing same-sex marriage was associated with a significant reduction in the rate of suicide attempts among high school students – and an even greater reduction among gay, lesbian and bisexual adolescents.

The Johns Hopkins Bloomberg School of Public Health researchers estimate that state-level, same-sex marriage policies were associated with more than 134,000 fewer adolescent suicide attempts per year. The study compared states that passed laws allowing same-sex marriage through Jan. 2015 to states that did not enact state-level legalization. A Supreme Court decision made same-sex marriage federal law in June of 2015.

The findings show the effect that social policies can have on behavior, the researchers say.

“These are high school students so they aren’t getting married any time soon, for the most part,” says study leader Julia Raifman, a post-doctoral fellow in the Department of Epidemiology at the Bloomberg School. “Still, permitting same-sex marriage reduces structural stigma associated with sexual orientation. There may be something about having equal rights – even if they have no immediate plans to take advantage of them – that makes students feel less stigmatized and more hopeful for the future.”

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Suicide is the second most common cause of death among people ages 15 to 24 in the United States. Suicide rates have been rising in the U.S., and data indicate that rates of suicide attempts requiring medical attention among adolescents increased 47% between 2009 and 2015. Gay, lesbian and bisexual high school students are at particular risk.

For the study, Raifman and her colleagues analyzed data from the Youth Risk Behavior Surveillance System, a survey supported by the Centers for Disease Control and Prevention. The data included 32 of the 35 states that enacted same-sex marriage policies between Jan. 1, 2004 and Jan. 1, 2015. The researchers used data from Jan. 1, 1999 to Dec. 31, 2015 to capture trends in suicide attempts five years before the first same-sex marriage policy went into effect in Massachusetts. They were also able to compare data with states that did not enact same-sex marriage laws. They conducted state-by-state analyses, comparing, for example, suicide attempt rates in a state like Massachusetts before same-sex marriage was legalized to the period right after.

State same-sex marriage legalization policies were associated with a seven percent reduction in suicide attempts among high school students generally. The association was concentrated in sexual minorities, with a 14 percent reduction in suicide attempts among gay, lesbian and bisexual adolescents. The effects persisted for at least two years. The states that did not implement same-sex marriage saw no reduction in suicide attempts among high school students.

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It’s unclear whether the political campaigns surrounding same-sex marriage legalization were behind the reduction in suicide attempts or the laws themselves. Still, they found that the reduction in suicide attempts wasn’t realized until after a law was enacted. In a state that would go on to pass a law two years in the future – when there was likely to be much conversation in the public about it – suicide attempts remained flat before passage.

While Raifman found that legalizing same-sex marriage appears to be positively associated with reducing suicide attempts, policies that take away rights or add to stigma could have the opposite effect.

“We can all agree that reducing adolescent suicide attempts is a good thing, regardless of our political views,” Raifman says. “Policymakers need to be aware that policies on sexual minority rights can have a real effect on the mental health of adolescents. The policies at the top can dictate in ways both positive and negative what happens further down.”

(Source: Johns Hopkins University Bloomberg School of Public Health)

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Brewery Offers Paid ‘Paw-ternity’ Leave for Employees With New Puppies

Dogs-Brew Dog

This brewery not only covers paid parental leave for their employees – they cover paid “paw-ternity” leave as well for their newly-adopted pups.

Brew Dog, the Scottish brewing company soon to open a new branch in Columbus, Ohio, is giving over 1,000 employees the opportunity to take a week’s worth of paid time off to spend with the new furry friends in their lives.

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“It’s not easy trying to juggle work and settle a new dog into your life, and many members of our crew have four-legged friends at home,” said company co-founder James Watt. “We wanted to take the stress out of the situation and let our teams take the time they need to welcome their new puppy or dog into their family.”

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Adorable Distracted Beagle At Westminster Dog Show is a Crowd Favorite (WATCH)

Westminster Dog Show beagle-Fox Sports

The announcers knew Mia the beagle wasn’t going to pick up any points with her distracted performance in the agility competition, but the adorable animal won hearts across the world by just being a dog.

“That was a delightfully entertaining run,” said one of the commentators of the world famous dog show, broadcast on Fox Sports.

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The breed judging for the 2017 Westminster Kennel Club’s 141st annual show begins February 20.

(WATCH the full video of Mia’s run below)

CLICK to Share Mia’s run with your Friends… (Photo – Fox Sports video)

25-Year-Old 911 Operator Meets Baby She Helped Deliver By Phone

Katie Farber-Youtube

At Katie Farber’s young age of just 25 years old, she effortlessly kept a cool head while helping a distressed husband deliver his child.

The 911 operator was persevering through her seventh shift as an emergency operator when a soon-to-be father called saying that his wife was in labor.

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Katie gave clear and concise instructions on how to deliver the child. It was two minutes after the young baby boy was successfully birthed that paramedics arrived.

Three weeks later, Katie was introduced to the adorable little boy whom she helped deliver.

(WATCH the sweet video below)

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Treatment Has Saved 77% of Cancer Patients Needing Amputations

Hello Stranger Running Club CC Johannes Poignant

Patients with a form of advanced malignant cancer in their arms or legs have typically faced amputation of the afflicted limb as the only treatment option. However, these researchers have found a technique that limits the application of chemotherapy to the cancerous region which preserves limbs in a high percentage of cancer patients.

The researchers used the treatment technique, known as regional chemotherapy with isolated limb perfusion (ILI), in 77 patients with treatment-resistant, locally advanced soft tissue sarcomas, and were able to salvage limbs in 77.9% of the cases.

The study, conducted over a 22-year period from 1994-2016, is the largest one to date of limb preservation using ILI for sarcoma.

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“Advocates for ILI in these patients would argue that, with similar long-term survival data and meaningful overall response rates, patients would much prefer a treatment that preserves the affected extremity to one that does not,” said lead study author John E. Mullinax.

ILI has historically been used primarily for melanoma of the extremities and the use of this technique in sarcoma is a more novel approach. Sarcoma is a rare type of cancer in the extremities with several different subtypes; the study patients who underwent ILI had 17 different subtypes of sarcoma.

The rationale for amputation of soft tissue sarcoma of the arm or leg has been to prevent the cancer from spreading to, or metastasizing to, other parts of the body. Dr. Mullinax noted that one concern with the use of ILI in these cancers is that it does not address distant metastatic disease. “The reality is that those patients who develop metastatic disease after amputation or ILI likely may already have distant microscopic disease at the time of the procedure, but the radiographic staging studies are not sensitive enough to detect it,” Dr. Mullinax said. “In this sense, the treatment of the extremity disease is not to the determinant of long-term survival.”

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In the study population, 19 patients had 21 procedures for upper-extremity disease and 58 patients had 63 infusions for lower-extremity disease. The results varied significantly for the two groups. The overall three-month response rate to ILI was 58%, but it was only 37% for those with upper-extremity disease vs. 66% for lower-extremity disease. Likewise, those who had upper-extremity sarcomas had a lower median overall survival than their lower-extremity counterparts, 27.9 months vs. 56.6 months. For the entire study population, the median overall survival was 44.3 months.

Entering the study, all the patients had sarcomas that could only be removed with an amputation, but afterward 30% had a complete response to ILI, many of these because patients were able to have a surgical procedure to remove the tumors without amputation. For those who eventually needed an amputation, the median time to do so was 4.5 months following ILI.

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The ILI technique involves circulating the chemotherapy agents melphalan and actinomycin D in the blood vessels of the affected area of the arm or leg, and the use of a tourniquet to block the chemotherapy drugs from circulating through the rest of the body, thus creating a closed circuit. The drugs circulate in the target area for 30 minutes, and then are flushed out before the tourniquet is removed and full circulation is restored. ILI for soft tissue sarcoma of the extremities can be repeated, whereas another procedure to administer chemotherapy to the arms or legs, hyperthermic isolated limb perfusion, requires an incision to openly cannulate the vessels and generally cannot be repeated, Dr. Mullinax explained.

“Most patients would prefer to have more time with their leg rather than face an amputation,” Dr. Mullinax said. “It’s known that for patients with soft-tissue sarcoma, the life-limiting disease is not in the extremity but it’s actually in the metastatic disease. An inoperable sarcoma of the thigh does not affect survival to the degree that metastatic disease in the lung does.”

(Source: American College of Surgeons)

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7-Year-old Applies For Job at Google, Gets Letter Back From CEO

Chloe Bridgewater's Letter-Submitted

Chloe Bridgewater might only be 7 years old, but her letter to the CEO of Google demonstrates she already has adult-sized ambition.

Entranced by the magic of her Kindle Fire, Chloe recently became interested in technology and robotics. Her father Andy suggested that she apply for a job at the beloved Silicon-valley company.

When he mentioned that employees also have special access to recreational slides and go-karts, Chloe was sold.

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The daughter wrote a heartfelt letter from her home in Hereford, England to Google CEO Sundar Pichai in California, ending the note by saying she has “only ever sent one other and that was to Father Christmas”.

She was delighted to find that she had received a response from Sundar earlier this week.

“Thank you so much for your letter. I’m glad that you like computer and robots, and hope that you will continue to learn about technology,” wrote Sundar. “I think if you keep working hard and following your dreams, you can accomplish everything you set your mind to – from working at Google to swimming in the Olympics.

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“I look forward to receiving your job application when you are finished with school! 🙂 ”

The letter has apparently invigorated Chloe to work even harder at one day working for the tech company, despite the years of primary school she has yet to complete.

Sundar Pichai Letter-Andy Bridgewater

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Cop Goes Above and Beyond For Stranded Student with Busted Car

Officer Borne and Busted Car-Submitted

Stranded on the side of a highway near a busy onramp stood an 18-year-old student with a tire blowout. Luckily, Officer Jason Borne saw the young man while on patrol.

The policeman pulled over to help the student change his tire since the youth didn’t have a jack.

“I began teaching the young man how to change his flat tire with the basics: put your emergency brake on, righty tighty, lefty loosey, where the jacking points were, etc.,” says Borne. “[But] once we got the destroyed tire off, we realized that the ‘spare’ tire that was thrown in with the purchase of the 16 year-old car was the wrong size and the nuts wouldn’t fit.”

Borne and his partner bought the student new tires and said that the “shocked look on his face” was all the payment they needed.

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Unfortunately, the student was still going to be driving an old car with unrepaired collision damage and an unaligned front end.

That’s why Officer Borne then created a GoFundMe page to ensure reliable transportation for the student. With the attention of social media, the campaign has already raised $6,900 —more than the original goal of $5,000.

“I want to get his alignment done at a minimum. Ideally, it would be even more incredible to fix the car, or even send him on to college with a more reliable mode of transportation,” says Borne. “I hope we can give this young man an inspiring display of community and philanthropy.”

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B Vitamins Offer Surprising Reduction in Schizophrenia Symptoms

B Vitamins-Wikipedia Commons

A review of worldwide studies has found that add-on treatment with high-dose b-vitamins – including B6, B8 and B12 – can significantly reduce symptoms of schizophrenia more than standard treatments alone.

Schizophrenia affects around 1% of the population and is among the most disabling and costly long term conditions worldwide. Currently, treatment is based around the administration of antipsychotic drugs.

Although patients typically experience remission of symptoms such as hallucinations and delusions within the first few months of treatment, long-term outcomes are poor; 80% of patients relapse within five years.

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The researchers reviewed all randomized clinical trials reporting effects of vitamin or mineral supplements on psychiatric symptoms in people with schizophrenia.

In what is the first meta-analysis carried out on this topic, they identified 18 clinical trials with a combined total of 832 patients receiving antipsychotic treatment for schizophrenia.

B-vitamin interventions which used higher dosages or combined several vitamins were consistently effective for reducing psychiatric symptoms, whereas those which used lower doses were ineffective.

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“Looking at all of the data from clinical trials of vitamin and mineral supplements for schizophrenia to date, we can see that B vitamins effectively improve outcomes for some patients,” said lead author Joseph Firth, based at the University’s Division of Psychology and Mental Health. “This could be an important advance, given that new treatments for this condition are so desperately needed.”

Also, the available evidence suggests that B-vitamin supplements may be most beneficial when implemented early on, as b-vitamins were most likely to reduce symptoms when used in studies of patients with shorter illness durations.

“This builds on existing evidence of other food-derived supplements, such as certain amino-acids, been beneficial for people with schizophrenia,” said co-author Jerome Sarris, Professor of Integrative Mental Health at Western Sydney University. “These new findings also fit with our latest research examining how multi-nutrient treatments can reduce depression and other disorders.”

The research team say more studies are now needed to discover how nutrients act on the brain to improve mental health, and to measure effects of nutrient-based treatments on other outcomes such as brain functioning and metabolic health.

(Source: University of Manchester)

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Are You Living a Meaningful Life? Here Are a Few Tips on How to Start

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Are you doing what matters most to you? Does your work give your life meaning?

I’m not asking whether you are happy, but whether your life has meaning. A study in the Journal of Positive Psychology examined attitudes toward happiness and meaning, and found that a meaningful life and a happy life overlap in certain ways, but are ultimately different.

“While happiness is an emotion felt in the here and now, it ultimately fades away, just as all emotions do,” wrote Emily Esfahani Smith about the study in The Atlantic. “The amount of time people report feeling good or bad correlates with happiness but not at all with meaning. Meaning, on the other hand, is enduring. It connects the past to the present to the future.”

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Another study confirmed this, she said. “People who have meaning in their lives, in the form of a clearly defined purpose, rate their satisfaction with life higher, even when they were feeling bad, than those who did not have a clearly defined purpose.”

Giving your work meaning can be a simple shift in perspective, as it was for me.

Back in the 1990s the focus of our company, Learning Strategies, was to sell more audio programs and enrollments. We were sales oriented as were most companies.

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Then we switched our mindset from selling to helping more people experience their potential, and two things happened. First, I felt more fulfilled and happier, and second, our business grew significantly. The level of meaning in my life increased considerably as did the success we enjoyed.

My colleague Stewart Emery and his co-authors of the book Success Built to Last interviewed two hundred of the world’s most successful people and uncovered the same experiences.

“Above all else, no matter where they have chosen to excel—in business, the arts, sports, social service, community, or family—each has achieved success by focusing on the things that matter most to them,” he said.

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“Enduringly successful people follow their hearts, aligning their thoughts and actions with their passions,” said Stewart. “They become energized by their work and stay on purpose and committed in the face of setbacks and challenges.”

I couldn’t agree with him more. During our company’s long-term success, there have been some extremely difficult times. But as long as we held fast to our vision to serve others, we really never had to worry. It fueled everything we did.

To create a life that matters to you, consider the following:

What gives your life meaning? What brings you the greatest joy? Loving what you do and who you are is the greatest motivator for building lasting success. Just shifting our company focus from sales to impacting people, gave me and our staff meaning, and it continues twenty years later. Is there a shift like that you can make?

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Are your thoughts toxic or supportive? Are negative thoughts and self-doubt or the criticism of others drowning out that voice inside of your head—that whisper or “silent scream” telling you what really matters? Learn to responsibly manage your thoughts in ways that keep you on track to your goals, despite obstacles or burdens you will undoubtedly face.

Are you taking action? What are you doing to bring you closer to your goals or attract into your life people and activities that will support you? While meaning drives success, meaning without action will get you nowhere.
When you align your thoughts and actions with what gives your life meaning, you magnify your passion and impart greater clarity to your purpose than ever before.

Pete Bissonette is author of the forthcoming novel, Breakfast Tea & Bourbon, wherein living a meaningful and joyous life is woven throughout the story. He is the president of Minneapolis-based Learning Strategies, a personal development training and publishing company founded in 1981. 

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Man Single-handedly Repopulated Butterfly Species in a City Using His Backyard

Pipevine Swallotail Butterflies-Tim Wong

Tim Wong may work as an aquatic biologist during the day, but when he is back on terra firma he tends to other wildlife: raising endangered butterflies in his backyard.

Studying butterflies had been a childhood hobby of Wong’s, so creating a backyard conservation area wasn’t a life-changing metamorphosis for him—but it certainly was for this species, which had vanished from the San Francisco skyline.

When he first learned of the predicament of the pipevine swallowtail, the 28-year-old swooped in to help by creating a screened backyard enclosure with ideal environmental conditions for the insect.

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He filled it with specific plants that the insects like to feed on. Then, he gathered a group of 20 different pipevine swallowtail caterpillars from nearby areas. As he carefully nursed the small tribe of precious insects, their numbers began to quickly multiply.

Now years later, the DIY butterfly breeder brings dozens of caterpillars to the San Francisco Botanical Garden’s “California Native” exhibit every week—and thanks to Wong’s efforts, the pipevine swallowtail has been successfully repopulated in the city for the first time in decades.

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Though the pipevine swallowtail isn’t technically endangered, the breathtaking species rapidly began disappearing from various areas around California as the state became more and more developed. Since they had vanished entirely from San Francisco, Wong had to collect his original group of caterpillars from private residents living in more vegetative areas.

Though backyard conservation isn’t his professional forte, Wong has claimed—and earned— the lofty mantle of “Butterfly Whisperer” on Instagram.

WATCH the video below…

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Watch Dancing Dads in Tutus Steal the Show in Students’ Ballet Class

Dad in Tutu-Youtube

These dads may not know a thing about ballet, but that didn’t stop them from putting their best foot forward and donning little pink tutus for the sake of their talented daughters.

The Philadelphia Dance Center in Pennsylvania hosted a parents dance day at their studio earlier this week.

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While the moms were shaking their stuff in the hip hop class, a number of daring dads attempted to do ballet with their girls.

They may look awkward attempting an arabesque, but the resulting video has made them stars of the dance season…

(WATCH the video below)

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Iowa City is Devoting 1,000 Acres to Saving Honeybees

Praire Sign-Cedar Rapids Parks and Recreation

As honeybee populations continue to dwindle in the United States, this small town in Iowa is starting a groundbreaking initiative to save the precious pollinators.

The 1,000 Acre Pollinator Initiative in Cedar Rapids is a campaign to populate 1,000 acres of the local area with wildflowers and prairie grasses essential to honeybee survival.

County park officials in collaboration with the Monarch Research Project hope that restoring the insect’s natural habitat will help combat the damaging effects of pesticides and climate change on honeybee populations.

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The project will begin in the spring with the seeding of 188 acres of unused public land, including park corners, golf courses, sewage ditches, water retention basins, and roadway medians. The seed mixture is a robust combination of 39 different native wildflower species and seven different prairie grasses. The initiative is projected to be completed over the course of five years.

The state has already allocated over $180,000 for the start of the project, with more fundraising expected in the coming years.

“When you convert it back to what was originally native Iowa, you’re going to help a lot more than just native pollinators,” Cedar Rapids Park Superintendent Daniel Gibbins told Popular Science.  “You’re helping birds, amphibians, reptiles, mammals—everything that’s native here relies on native vegetation.”

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Russian Scientists Have Successfully Slowed Down the Aging Process

Lab Mouse-The A.N. Belozersky Institute Of Physico-Chemical Biology

A group of Russian and Swedish scientists have just published a breakthrough paper, explaining how they successfully slowed down the aging process in a group of mice.

The major goal of the study was to investigate the role of mitochondria in the process of aging in organisms. Importantly, scientists made an attempt to slow down aging using a novel compound: artificial antioxidant SkQ1 precisely targeted towards the mitochondria.

Starting from a certain age, one group of mice was treated with small doses of SkQ1 added into their drinking water. Per scientists’ hypothesis, the compound would protect animal cells from the toxic byproducts of mitochondria known as free radicals, which is a reactive oxygen species. Another group of animals served as a control group receiving pure water.

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Differences between the two groups became obvious as the mice continued to age. Animals in the control group aged rapidly as expected. They were losing weight, their body temperature decreased, severe curvature of the spine (as a result of osteoporosis) and alopecia were developing, their skin became thinner, and in case of females estrus cycle was impaired. Finally, their mobility and oxygen consumption were decreased. The development of all these typical traits of aging was dramatically decelerated in the group treated with SkQ1. Some of the aging traits did not appear in that group at all.

Professor Vladimir Skulachev, the creator of SkQ1 molecule design and co-author of this study, says: “This work is quite valuable from both theoretical and practical points of view. First, it clearly demonstrates the key role of mitochondrially produced reactive oxygen species in the process of aging in mammals. At the same time, our study opens the way to the treatment of aging with mitochondrially targeted antioxidants.”

Prof. Skulachev’s project is now developing a set of pharmaceuticals based on SkQ1 molecule. The first drug – Visomitin eye drops – is already approved and marketed in Russia and passed phase 2 clinical trials in the US. The next pharmaceutical product in the project’s pipeline is an oral form of SkQ1 (similar to the one used in the aforementioned experiments). It is now in the process of clinical trials in Russia. In case of positive results of these trials, such “anti-aging” drug can be approved for systemic indications in 2-3 years.

(Source: Lomonosov Moscow State University)

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Shatner and Retailer Make Sure Boy With Autism Always Has Favorite Food

Everett Botwright-Facebook

Because Everett Botwright has autism, the 6-year-old recently started refusing to eat anything if it wasn’t the meal that stole his heart: Star Wars themed Kraft macaroni and cheese dinners.

Everett’s family became especially distressed when – after they had already bought all of the boxes that they could carry – their local Walmart discontinued the special product.

The youngster’s father Reed Botwright took to social media in search of anyone who could direct them to a store that carried the limited edition meals.

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“He’s on the autism spectrum and one of his quirks revolves around food,” Reed wrote on Instagram. “It’s a struggle to get him his essential nutrients, and unlike most kids, no amount of ‘tough love’ or ‘no treats until you eat your veggies’ will work to coerce him to expand his diet.”

One day later and who should step in to help but the hallowed Star Trek actor William Shatner.

Captain Kirk sent a tweet to Kraft on Tuesday, asking: “Can you possibly help? Even if you still have just the shaped macaroni they can use current product for cheese sauce.”

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While Kraft responded to the message saying that they were working on a way to help, a local supermarket who had reportedly received “an influx of customers come into the store asking for Star Wars Kraft Dinner” heard about the Botwright family’s dilemma.

The Real Canadian Superstore in Vancouver ordered 400 boxes of Star Wars Kraft Dinners from one of their other stores to be delivered to Everett on Friday – which amounts to over one year’s supply of the special meals.

“The outpouring of support has been amazing,” said Reed. “And overwhelming. There are so many wonderful and caring people out there. My faith in humanity has been thoroughly restored!”

(WATCH the video below)

 

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Rare Gray Owl Spotted in Utah for First Time in 30 Years

Gray Owl-Vimeo

The Great Gray Owl is the biggest owl in the world – and it hasn’t been seen in Utah for 30 years.

Utah resident Amber Watkins-Olpin was driving through Mountain Green last week on her way to work when she saw a huddle of residents gathered on the side of the road. Curious as to what the commotion was about, she pulled over to find that the crowd was standing in awe of the enormous bird, who was perched calmly and unflinchingly on the ground.

A few hours laters on her way back from work, Amber saw that the owl was still there, only now perched in a tree.

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Amber went home, gathered her family, and returned to the owl’s spot. Her husband, Chris Olpin of Dreamcastar Productions, brought his camera along with him too.

“I was lucky enough to capture this majestic great grey owl today,” says Chris. “Owls are very symbolic to me. The last time this type of owl has been sighted in Utah was over 25 years ago.”

And the Great Gray Owl is majestic indeed. Females and males typically range a little over two feet in length with a wingspan of up to five feet. Though they typically don’t reside in Utah, harsh winter seasons can push them farther south during migration.

The footage that Chris captured was verified by Utah Division of Wildlife Resources biologist, Russell Norvell, program coordinator of the Avian Conservation, according to KSL.

(WATCH the video below)

 

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Shirt Containing $8,000 Returned to Woman Who Accidentally Gave it Away

Hoffman and Goodwill Worker-Youtube

Linda Hoffman was simply trying to clean out her and her husband’s closets of old clothes – she had no idea that she was giving away a small fortunate in the process.

Her husband, Bob Hoffman, had been using one of his old shirts to hide his savings. Over the course of six years, he had squirreled away over $8,000 in the hopes of one day surprising Linda with a vacation to Italy.

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When the couple realized that Linda had accidentally donated the shirt to Goodwill two days later, they rushed to the nearest store in Placentia, California.

Employees spent all day looking for the lost shirt with no luck. The next day, however, Caitlin Mulvihill finally dug it out of one of the bins.

The Hoffman’s relief and gratitude for finding the lost shirt was unparalleled.

(WATCH the video below)

 

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Gene Therapy Could Save Thousands of Dogs from Muscle-wasting Disease

Gene Therapy Dogs-Martin Childer Lab

Work on gene therapy is showing significant progress for restoring muscle strength and prolonging lives in dogs with a previously incurable, inherited neuromuscular disease.

The disease arises from a mutation in genes that normally make a protein, called myotubularin, essential for proper muscle function. Puppies with this naturally occurring mutation exhibit several features of babies with the same defective gene. The rare disorder, called myotubular myopathy, or MTM, affects only males. It causes fatal muscle wasting. Both dogs and boys with the disease typically succumb in early life due to breathing difficulties.

For decades, researchers have struggled to find suitable treatments for genetic muscle diseases like this one. Four collaborating research groups in the United States and France found a way to safely replace the disease-causing MTM gene with a healthy gene throughout the entire musculature of affected dogs.

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Their paper reports that diseased dogs treated with a single infusion of the corrective therapy were indistinguishable from normal animals one year later.

“This regenerative technology allowed dogs that otherwise would have perished to complete restoration of normal health,” said Dr. Martin K. “Casey” Childers, UW Medicine researcher and physician.

Gene therapy holds the promise to treat many inherited diseases. To date, this approach has not been widely translated into treatment of skeletal muscle disorders.

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“We report here a gene therapy dose-finding study in a large animal model of a severe muscle disease where a single treatment resulted in dramatic rescue,” said Childers. The findings demonstrate potential application across a wide range of diseases and broadly translate to human studies. The data supports the development of gene therapy clinical trials for myotubular myopathy, the researchers concluded.

(Source: University of Washington Health Sciences)

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Heartfelt Memories May Be More Effective Than Shaming to Help Smokers Quit

Cigarette Smoking-Public Domain

Rather than inciting fear, this new study says that anti-smoking campaigns should tap into smokers’ memories and tug at their heartstrings instead of using scare tactics.

Researchers from Michigan State University say that advertisers often use nostalgia-evoking messages to promote consumer products, and that tactic could be just as effective in encouraging healthy behaviors, argue Ali Hussain, a doctoral candidate in the School of Journalism, and Maria Lapinski, professor in the Department of Communication.

“A lot of no-smoking messages are centered around fear, disgust and guilt,” Hussain said. “But smokers often don’t buy the messages and instead feel badly about themselves and the person who is trying to scare them.”

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According to the Centers for Disease Control and Prevention, cigarette smoking is the leading cause of preventable disease in the United States, accounting for one of every five deaths. Smoking rates have declined, but in 2015, 15 of every 100 adults were active smokers.

Despite the health risks, a key hurdle for health communicators is rejection and avoidance of messages, Lapinski said.

Hoping to find a solution, researchers conducted a study of smokers, ages 18 to 39, exposing some to a nostalgic public service announcement Hussain created and some to a control message.

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Those who viewed the PSA reported greater nostalgic emotions and displayed stronger negative attitudes toward smoking, especially women.

Starting with images of childhood memories, the PSA script includes phrases such as, “I remember when I was a boy” and “I miss the simplicity of life, being outside on a warm summer night,” making references to familiar smells and tastes from bygone days. It ends with the narrator remembering when someone introduced him to cigarettes and a call to action.

Nostalgia-themed PSAs play off consumers’ most cherished and personal memories, so they feel more engaged, the researchers said. And that nostalgic thinking influences attitudes and behaviors.

“Our study, which to our knowledge is first of its kind, shows promise for using nostalgic messages to promote pro-social behaviors,” Lapinski said. “We know that policy and environmental changes have an influence on smoking and this study indicates persuasive messages can influence smoking attitudes.”

(Source: Michigan State University)

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Puppy Rescued From Well After 11 Days is Adopted by Firefighters Who Saved It (WATCH)

Firefighters and Puppy-Istanbul Fire Department

This sweet puppy who enraptured the nation may not have made it out of this gaping well if it weren’t for an entire community making sure that it survived.

Residents of Beykoz, Turkey heard whimpering coming from a nearby well that plunged 200 feet into the earth. After confirming that there was a small dog trapped at the bottom, firefighters, rescue crews, and animal rescue teams flooded the area to assess the situation.

A camera that was lowered into the hole showed that the canine looked frightened, but was alive and relatively unharmed.

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Then the crews established a tent surrounding the hole to make sure that no rain or water would flood the well.

Puppy Trapped in Well-Barış Şengün

Over the course of the following 11 days, the teams lowered dog food into the hole to make sure it didn’t starve. They could not, however, figure out how to get the puppy out of the well.

The crew attempted using everything from rope and pulleys, to a robotic arm constructed by local high school students – but nothing worked.

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As the story gained more and more national attention, it finally caught the eye of Energy Minister Berat Albayrak who offered the services of the Turkish Hard Coal Enterprises.

Rescuing Dog From Well-Istanbul Fire Department

The team was finally able to mechanically lasso the 3-month-old pup and haul it to safety amidst cheers from everyone present for the suspenseful rescue.

The dog was taken to the veterinarian where he was deemed healthy and unharmed by the ordeal. Local firefighters announced that they would be adopting the pup who has since been dubbed “Kuyu” – which is Turkish for “well”.

(WATCH the video below)

 

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Guy Sacrifices Tesla to Save Unconscious Driver, Elon Musk Offers to Repair It

Tesla Car Incident-Feuerwehr München

Even though a Tesla Model S is worth thousands of dollars, this guy didn’t hesitate to sacrifice it in order to do the right thing and save a man’s life.

41-year-old Manfred Kick was driving down the Autobahn – a federally controlled highway with no mandated speed limit – when he saw a Volkswagen swerving dangerously across the road. Curious, Manfred peered into the car’s windows only to find that the driver had fallen unconscious against the steering wheel.

Manfred pulled his Model S in front of the Volkswagen and braked until both of the cars came to a halt.

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He then ran to the man’s side and performed first aid until emergency medical technicians arrived and took the unconscious driver to a hospital in Munich, Germany.

Officials said that though the man had reportedly suffered a stroke of some kind, he is currently in stable condition.

Manfred, who was then stuck with over $10,000 in repair costs, was in turn rescued by none other than the Tesla company CEO Elon Musk.

“Congrats to the Tesla owner who sacrificed damage to his own car to bring a car with an unconscious driver safely to a stop!” Musk wrote on Twitter. “In appreciation, Tesla is providing all repair costs free of charge and expedited.”

Drive This Story Over To Your Friends: Click To Share (Photo by Feuerwehr München)