This adorable soccer match between three professional soccer players and a team of delighted Chinese children is the perfect example of how quantity can triumph over quality.
Tottenham Hotspur star players Harry Kane, Dele Alli, and Erik Lamela participated in an exhibition game against 100 kids aged 6 to 10 in order to celebrate their pre-season games in China.
Despite how the pro players reassured spectators that they would not go easy on their pint-sized competitors, the 10-minute game in Shanghai ended in a one-to-one draw.
When asked about the difficulty of the game, Alli amusedly gave credit to the “ruthless” kids by saying that they definitely had “bodies behind the ball”— but the opposing teams did not let their action-packed match get in the way of their newly-ignited friendships.
“Another tough challenge,” Alli told reporters with a smile. “Not quite like playing in the Premier League … but it’s exciting and it’s nice to have a bit of fun with them.”
As a reward for the children’s tenacity and support, Alli, Kane, and Lamela made sure to sign shirts and high-five all the youngsters after the harrowing game.
(WATCH the endearing game footage below)
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Despite how cataracts are the most common and treatable form of blindness, there are hundreds of thousands of people suffering from the condition in Nepal every day—and that’s why this one doctor has been working tirelessly to restore their vision.
Dr. Sanduk Ruit is an ophthalmologist who has trekked all over Nepal in order to perform cataract surgeries on blind people living in remote areas. With surgical equipment in tow, Ruit has embarked on 7-day hikes solely for the purpose of treating blindness.
Since Ruit first dedicated himself to treating blindness across his home country, he has personally restored vision to over 130,000 people.
Ruit is also the executive director of the Tilganga Institute of Ophthalmology, a Kathmandu-based nonprofit that caters to as many as 1 million patients.
According to the eye doctor, about 90% of the world’s blind population is located in Nepal. This is partially because there are fewer eye doctors in countries that are less developed, and also because cataract lenses previously had to be imported from international manufacturers, which upped the cost of the lenses to as much as $300.
Since Ruit and his organization have helped to source cataract lenses locally, however, they now cost just $3 a pop.
(WATCH the inspiring video below) – Photo by Great Big Story
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Rather than using milk cartons to raise awareness for missing persons, a New Jersey pizzeria has come up with a clever new way to help search for lost pets.
Angelo’s Pizza restaurant in Matawan has started attaching lost animal flyers to their pizza boxes as a means of helping frantic pet owners reunite with their furry friends.
The owner of the restaurant, John Sanfratello, said he got the idea for the initiative after he saw a neighbor’s Facebook post about a missing cat.
Sanfratello was particularly struck by the post because the cat looked just like his own feline companion who once went missing for an entire week.
He then published a note to the pizzeria’s Facebook page telling pet owners that he would begin attaching their missing animal flyers to all of his pizza boxes free of charge.
“We don’t care if owners are customers or not, I’m concerned about how we can help,” Sanfratello told Good Morning America. “This is a small gesture on our part, but [pets] are family members after all.”
Since Sanfratello publicized the restaurant’s missing pet initiative on Facebook, they have handed out dozens of flyers for three missing pets in the Matawan area. Additionally, Sanfratello has several family members who have been inspired to hand out missing animal flyers from their own New Jersey restaurants.
“We need to find as many pets as we can,” he told GMA. “And we need to raise awareness, so that hopefully more businesses become involved on a local level.”
(WATCH the news coverage below)
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When a 32-year-old driver became trapped in his overturned car on the highway, a dozen Good Samaritans rushed to his aid.
The driver, Orlando Hernandez, lost control of his Ford pickup truck as he was driving on I-88 in Chicago earlier this week.
Hernandez had been driving in the left lane when the tread of his tires tore off and sent his truck spinning onto its roof and onto the shoulder of the highway.
Upon seeing the disaster unfold, several other drivers stopped their cars and ran to his rescue.
With the help of a few nearby construction workers, the group of rescuers managed to push the truck onto its side, break the safety glass, and free Hernandez from his seatbelt—all before the ambulance crew arrived onto the scene to whisk him off to the hospital.
Apart from a few minor injuries that he endured from the incident, Hernandez says that he is in surprisingly good shape—and he is overwhelmed with gratitude for the people who came to his rescue.
“You know how there’s terrible things happening and people lose faith in things, faith in the world? But seeing that, that sort of restores that goodness in your heart,” Hernandez told WLS-TV.
(WATCH the news coverage below) – Photo by WLS-TV
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Quote of the Day: “Humility is not thinking less of yourself, it’s thinking of yourself less.” – C.S. Lewis
Photo: by Luigi Andreola, CC license
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This story was submitted as a nomination to the Reader’s Digest “Top 50 Nicest Places in America” contest: a crowd-sourced effort to uncover nooks where people are still kind and respectful in an era of cultural and political divides. Be sure and vote for which story you think should be nominated as the Nicest Place by visiting the Reader’s Digest website.
Photo by Christian Hinkle/Shutterstock
A compassionate pizzeria owner had a reputation for ensuring that his Amish neighbors never went hungry—so when his rural restaurant later burned down, they were sure to repay their debt.
Just before Christmas in 2013, Delta Pizza burned to the ground. It was a big deal in the tiny hamlet of Delta, Pennsylvania. The remote town of about 700 people on the Maryland border doesn’t have a lot of options when it comes to where to eat.
Then, something magical happened.
“We’re cleaning up and I heard this noise outside, like a train was coming through,” says Sal Ferranti, the owner since his father, Guiseppe, died in 1999. “It was 30 Amish men in buggies. They helped for one day with the demolition of the building.”
As it turns out, they were just returning the favor. For years, Sal had been making sure that extra food from catering jobs would make it to Amish folks who needed it.
In fact, the whole town pitched in to help Sal reopen. They were paying him back too, for his family’s 30 years of serving charity and kindness along with their slices. On snow days, kids gather to eat free pizza and watch cartoons until their parents get home from work. About two times a month, people gather for fundraisers for various causes—all while enjoying donated pizza, of course. Recently, Sal came across a homeless man in town, and after publishing just one Facebook post, he later got him a job and a place to stay.
“That’s just the kind of guy Sal is,” says Deborah Shade, who nominated Delta Pizza for the Nicest Places competition. “Anybody that comes to him with any kind of request, he’s there for them.”
Turns out, he learned it from his dad. In 1984, when the family arrived from Italy, they had nothing and didn’t know the language. After getting citizenship in 1987, Guiseppe bought flags for every flagpole in town—and they fly to this day. It was Guiseppe who started holding fundraisers, getting involved in civic life, and making sure to help anyone who needed it.
So after Delta Pizza’s grand reopening in 2015, Sal knew he had to continue his father’s compassionate legacy. That’s why each year he chooses a different Amish family who helped with the demolition and spends two hard days laboring on their farm, picking tomatoes or tobacco, or whatever else they need done.
“They were so giving and so helping, and I have to give back to them—to everyone who helped,” Sal says.
Reprinted with permission from Reader’s Digest. To learn more about GNN’s part in searching for the Top 10 Nicest Places, click here.
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Photo by Eran Elinav/Weizmann Institute of Science
Scientists are quickly discovering that our gut microbiomes may hold the key to a vast amount of health issues—including ALS.
Researchers at the Weizmann Institute of Science have shown in mice that intestinal microbes, collectively termed the gut microbiome, may affect the course of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease.
As reported this week in Nature, progression of an ALS-like disease was slowed after the mice received certain strains of gut microbes or substances known to be secreted by these microbes—and results suggest that these findings are likely applicable to human patients with ALS.
“Our long-standing scientific and medical goal is to elucidate the impact of the microbiome on human health and disease, with the brain being a fascinating new frontier,” says Professor Eran Elinav of the Immunology Department.
The scientists started out demonstrating in a series of experiments that the symptoms of an ALS-like disease in transgenic mice worsened after these mice were given broad-spectrum antibiotics to wipe out a substantial portion of their microbiome. Additionally, the scientists found that growing these ALS-prone mice in germ-free conditions (in which, by definition, mice carry no microbiome of their own), is exceedingly difficult, as these mice had a hard time surviving in the sterile environment. Together, these results hinted at a potential link between alterations in the microbiome and accelerated disease progression in mice that were genetically susceptible to ALS.
Photo by Eran Elinav/Weizmann Institute of Science
Next, using advanced computational methods, the scientists characterized the composition and function of the microbiome in the ALS-prone mice, comparing them to regular mice. They identified 11 microbial strains that became altered in ALS-prone mice as the disease progressed or even before the mice developed overt ALS symptoms. When the scientists isolated these microbial strains and gave them one by one—in the form of probiotic-like supplements—to ALS-prone mice following antibiotic treatment, some of these strains had a clear negative impact on the ALS-like disease. But one strain, Akkermansia muciniphila, significantly slowed disease progression in the mice and prolonged their survival.
To reveal the mechanism by which Akkermansia may be producing its effect, the scientists examined thousands of small molecules secreted by the gut microbes. They zeroed in on one molecule called nicotinamide (NAM): Its levels in the blood and in the cerebrospinal fluid of ALS-prone mice were reduced following antibiotic treatment and increased after these mice were supplemented with Akkermansia, which was able to secrete this molecule.
To confirm that NAM was indeed a microbiome-secreted molecule that could hinder the course of ALS, the scientists continuously infused the ALS-prone mice with NAM. The clinical condition of these mice improved significantly. A detailed study of gene expression in their brains suggested that NAM improved the functioning of their motor neurons.
Finally, the researchers examined the microbiome and metabolite profiles of 37 human ALS patients and compared them to those of family members sharing the same household. A detailed genomic analysis suggested that the gut microbiomes of ALS patients were distinct in composition and functional features from those of healthy controls. In particular, numerous microbial genes involved in the synthesis of NAM were significantly suppressed in ALS patients.
An analysis of thousands of small molecules in the blood also revealed a distinct pattern in ALS patients as compared to controls. Here too, many of the intermediary molecules involved in the NAM synthesis were altered in the blood of ALS patients. When the researchers tested the levels of NAM itself, they found these to be significantly reduced in both the blood and the brain of 60 human ALS patients as compared to controls. Moreover, there was a correlation between reduced NAM levels and the degree of muscle weakness in the patients.
“These findings are only a first step towards achieving a comprehensive understanding of the potential impact of the microbiome on ALS,” Elinav says, “but they suggest that in the future, various means of altering the microbiome may be harnessed for developing new therapeutic options for ALS.”
Reprinted from the Weizmann Institute of Science
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These four American brothers traveled to Ireland last week as visitors—but since they rescued a little girl and her father from drowning in the ocean, they are now leaving the country as heroes.
LISTEN to the inspiring story told on the radio by our GNN founder (in the Good News Guru podcast below) or READ the full story below…
Photo by Juliana Butler
Eoghan, Walter, and Declan Butler had traveled to the Emerald Isles from Washington D.C. with their brother-in-law Alex Thomson in order to attend their grandfather’s funeral.
The young men had been preparing to enjoy a relaxing afternoon on Portmarnock Beach when they heard someone calling for a lifeguard.
A 6-year-old girl on a flotation device had been swept out to sea by a rogue current when her father started yelling for help.
Eoghan, Declan, and Alex immediately sprinted into the ocean to rescue the girl while Walter stayed on shore in case someone needed CPR.
Since the youngster had already drifted half a mile away from the shore, the three brothers were forced to swim for 25 minutes in order to reach her—a harrowing feat, even for three athletic young men.
Once they reached the girl, the brothers then took turns swimming on their backs in order to tow the girl’s flotation device back to shore on their chests.
Upon successfully bringing the girl back to dry land, Eoghan and Declan noticed that the girl’s father was still in the water after he had put on a life vest to swim out and help with the rescue mission. The twin brothers then plunged back into the water and rescued the struggling father as well.
Though the young men felt relieved to have rescued the father-daughter-duo, they felt particularly emotional when they were visited by the little girl’s mother the very next day.
“Seeing her jump around, kiss her mom, that was actually amazing,” Declan told The Washington Post.
Furthermore, the boys later realized that their rescue had taken on a serendipitous meaning of its own: they had rescued the little girl on the exact same day that the brother of their deceased grandfather had drowned several decades ago.
“It’s kind of like this godly, guardian angel kind of feeling,” mused Walter, “that the same day he drowned 64 years ago is the day we actually saved the life of a 6-year-old girl.”
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In a sweeping show of bipartisan support, the US House of Representatives passed a new piece of legislation that is designed to put a stop to annoying robocalls once and for all.
The aptly-named “Stopping Bad Robocalls Act”, which was first introduced to the House last month, was approved this week in a landslide 429 to 3 vote.
The legislation is being lauded as a much-needed response to annoying robocalls after a February report from the FCC stated that there were over 5.7 million “Do Not Call” complaints from American consumers in 2018, over 3.7 million of which were classified as unwanted robocalls.
Thankfully, some of the bill’s key measures include requiring phone carriers to implement call authentication technology so consumers can trust their caller ID again; directing the FCC to take action against unwanted calls and enact safeguards so companies can’t abuse robocall exemptions; and ensuring the FCC has the authority and the tools to take strong, quick action when it tracks down robocallers.
Additionally, the measure will extend the statute of limitations from one year to three—and in some instances four—for callers violating robocall prohibitions.
The bill was introduced by two Democratic and two Republic representatives who issued a statement on the legislation’s approval this week.
“Today, the House of Representatives voted to restore Americans’ confidence in the telephone system and put consumers back in charge of their phones,” reads the statement. “We’re proud of the strong support our bipartisan Stopping Bad Robocalls Act received this afternoon and look forward to working with our colleagues in the Senate to produce a bill that the President can sign into law. The American people are counting on us to help end the robocall epidemic, and we will deliver for them.”
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A Japanese man’s sweet note for his American neighbors was shared across the internet after the appreciative family posted a photo of the letter to Reddit back in 2013.
Reddit user Theresa52 says that she and her husband had moved to Yokosuka after he had been stationed at the nearby Navy base. Upon moving into their new neighborhood, they set about delivering beer and chocolate to each of their neighbors—including a man named Hiroshi Yamashita.
A few hours later, Yamashita visited the American family’s home and presented them with toilet paper, stuffed animals for their daughter, and a note.
The note read “I can’t speak English. Thank you for the present. My name is Hiroshi Yamashita. I’m 52 years old. [I’m divorced] and I live alone.”
Though the rest of the letter had some translation letters, Theresa inferred that the man was asking whether her husband was in the Navy and expressing his hope that the family would appreciate the toilet paper and toys.
At the end of the note, Yamashita said: “Thank you for your friend operation.”
Though he may have been thanking the family for their gesture of friendship, other internet users assume that he was referring to Operation Friendship, which was the United States’ response to the 2011 earthquake in Japan.
Needless to say, Theresa and her husband were in awe of the heartfelt note.
“It was adorable! We had brought him a six pack and some chocolate and tried to introduce ourselves to him,” wrote Theresa. “A couple hours later he brought over this letter with a pack of toilet paper and some stuffed animals for our daughter.
“Yamashita wrote this note himself with some help from a translate app. His mom dated an American Sailor when Yamashita was a child so he knew a small amount of English.
“We were so impressed with his handwriting and we were totally not expecting a letter or a gift in return. Our introduction to him was a mix of Japanese words and pointing to Google Translate on our phone all while trying to hand him our gifts.”
With several thousand Reddit users vying for an update on Theresa’s new friendship with her neighbor, she later published a photo of her daughter enjoying her new toys—all courtesy of Yamashita.
“[Yamashita] will be getting more presents,” she added. “We never expected anyone to be so nice back to us.”
It has been six years since Theresa originally published a photo of the note to Reddit, but she recently made a post about how her friendship with Yamashita continued after their original interaction.
“Yamashita was a great neighbor! We did have daily morning chats,” she mused. “I had four elderly male neighbors who were all so sweet.
“We all exchanged gifts and food regularly for the four years I lived there. We would go to neighborhood festivals and have dinners together as well. I miss them all and think about them often.
In short, Theresa says that they did indeed end up sharing “a wonderful friend operation” of their own.
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Quote of the Day: “We must learn to regard people less in the light of what they do or omit to do, and more in the light of what they suffer.” – Dietrich Bonhoeffer
Photo: by Theophilos Papadopoulos, CC license
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Keven Walgamott and the LUKE Arm – Photo by University of Utah Center for Neural Interfaces
Photo by Dan Hixson/University of Utah College of Engineering
Thanks to a groundbreaking new technological accomplishment, amputee Keven Walgamott had a good “feeling” about using his new robotic arm to pick up an egg without crushing it.
What seems simple for nearly everyone else can be more of a Herculean task for Walgamott, who lost his left hand and part of his arm in an electrical accident 17 years ago. When he picked up the egg, however, he was testing out the prototype of a high-tech prosthetic arm with fingers that can not only can move, but also move with his thoughts—and thanks to a biomedical engineering team at the University of Utah, he “felt” the egg well enough so his brain could tell the prosthetic hand not to squeeze too hard.
That’s because the team, led by University of Utah biomedical engineering associate professor Gregory Clark, has developed a way for the “LUKE Arm” (so named after the robotic hand that Luke Skywalker received in Star Wars: The Empire Strikes Back) to mimic the way a human hand feels objects by sending the appropriate signals to the brain.
Their findings were published in a new paper co-authored by U biomedical engineering doctoral student Jacob George and other colleagues in the latest edition of the journal Science Robotics.
“We changed the way we are sending that information to the brain so that it matches the human body. And by matching the human body, we were able to see improved benefits,” George says. “We’re making more biologically realistic signals.”
That means an amputee wearing the prosthetic arm can sense the touch of something soft or hard, accurately understand how to pick it up, and perform delicate tasks that would otherwise be impossible with a standard prosthetic with metal hooks or claws for hands.
“It almost put me to tears,” Walgamott says about using the LUKE Arm for the first time during clinical tests in 2017. “It was really amazing. I never thought I would be able to feel in that hand again.”
Keven Walgamott and the LUKE Arm – Photo by University of Utah Center for Neural Interfaces
Walgamott, a real estate agent from West Valley City, Utah, and one of seven test subjects at the University of Utah, was able to pluck grapes without crushing them, pick up an egg without cracking it, and hold his wife’s hand with a sensation in the fingers similar to that of an able-bodied person.
“One of the first things he wanted to do was put on his wedding ring. That’s hard to do with one hand,” says Clark. “It was very moving.”
How those things are accomplished is through a complex series of mathematical calculations and modeling.
The LUKE Arm has been in development for some 15 years. The arm itself is made of mostly metal motors and parts with a clear silicon “skin” over the hand. It is powered by an external battery and wired to a computer.
Meanwhile, the University of Utah team has been developing a system that allows the prosthetic arm to tap into the wearer’s nerves, which are like biological wires that send signals to the arm to move. It does that thanks to an invention by called the Utah Slanted Electrode Array. The Array is a bundle of 100 micro-electrodes and wires that are implanted into the amputee’s nerves in the forearm and connected to a computer outside the body. The array interprets the signals from the still-remaining arm nerves, and the computer translates them to digital signals that tell the arm to move.
But it also works the other way. To perform tasks such as picking up objects requires more than just the brain telling the hand to move. The prosthetic hand must also learn how to “feel” the object in order to know how much pressure to exert because you can’t figure that out just by looking at it.
First, the prosthetic arm has sensors in its hand that send signals to the nerves via the Array to mimic the feeling the hand gets upon grabbing something. But equally important is how those signals are sent. It involves understanding how your brain deals with transitions in information when it first touches something. Upon first contact of an object, a burst of impulses runs up the nerves to the brain and then tapers off. Recreating this was a big step.
“Just providing sensation is a big deal, but the way you send that information is also critically important, and if you make it more biologically realistic, the brain will understand it better and the performance of this sensation will also be better,” says Clark.
To achieve that, Clark’s team used mathematical calculations along with recorded impulses from a primate’s arm to create an approximate model of how humans receive these different signal patterns. That model was then implemented into the LUKE Arm system.
In addition to creating a prototype of the LUKE Arm with a sense of touch, the overall team is already developing a version that is completely portable and does not need to be wired to a computer outside the body. Instead, everything would be connected wirelessly, giving the wearer complete freedom.
Clark says the Utah Slanted Electrode Array is also capable of sending signals to the brain for more than just the sense of touch, such as pain and temperature, though the paper primarily addresses touch. And while their work currently has only involved amputees who lost their extremities below the elbow, where the muscles to move the hand are located, Clark says their research could also be applied to those who lost their arms above the elbow.
Clark hopes that in 2020 or 2021, three test subjects will be able to take the arm home to use, pending federal regulatory approval.
Reprinted from the University of Utah
(WATCH the arm in action in the video below)
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This story was submitted as a nomination to the Reader’s Digest “Top 50 Nicest Places in America” contest: a crowd-sourced effort to uncover nooks where people are still kind and respectful in an era of cultural and political divides. Be sure and vote for which story you think should be nominated as the Nicest Place by visiting the Reader’s Digest website.
Photo by the Fugees Academy
This non-traditional school uses soccer to help refugees learn, and it has a 100% college acceptance rate.
In 2019, every single student of the graduating class at the Fugees Academy in Clarkston, Georgia, was accepted into college, and every single one of them was the first in their family to make it past middle school.
It’s a point of pride for the few schools that manage it. For Fugees, it’s extra impressive given the struggles faced by some of its students.
Established in 2004, the school is uniquely designed to help refugee children thrive. Founder Luma Mufleh, who fled her native Jordan and was given political asylum in the United States in 1999, got the idea when she stumbled upon some boys playing street soccer. She joined their game, and soon the boys—refugees from Liberia, Sudan, and Afghanistan—opened up with their stories. They had fled the horrors of war and famine and were struggling in America, where they weren’t getting the attention they needed to succeed in school.
Mufleh asked herself what she would do if these were her kids. “What’s really awesome about this country is that you can build solutions to problems,” she says.
So she sought out the students with the greatest academic need and used soccer as a way in. At Fugees, all 90 kids play soccer every day; they read about soccer; they write papers comparing and contrasting the styles of Messi and Ronaldo. Each pupil reads his or her report card to the entire school, and if a grade is slipping, the student body must decide how they, together, will get that grade back up.
Photo by Fugees Academy
“We want them to see that there’s no shame in struggling,” Mufleh says. “We’re going to help you no matter what.”
One Iraqi pupil, who survived kidnapping, bombing, and other hardships, recently wrote a brief biographical essay reading: “I attend a small private school called the Fugees Academy—and I’m sad when we get days off during snowstorms and holiday breaks.”
Fugees recently opened a second school, in Ohio, with a third one soon to follow.
Reprinted with permission from Reader’s Digest. To learn more about GNN’s part in searching for the Top 10 Nicest Places, click here.
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Medical marijuana is quickly being recognized as a viable alternative for pain relief—and now for the first time ever, researchers have uncovered exactly how the cannabis plant creates important pain-relieving molecules that are 30 times more powerful at reducing inflammation than Aspirin.
The discovery, which was made by researchers from the University of Guelph, unlocks the potential to create a naturally derived pain treatment that would offer potent relief without the risk of addiction of other painkillers.
“There’s clearly a need to develop alternatives for relief of acute and chronic pain that go beyond opioids,” said Professor Tariq Akhtar, Department of Molecular and Cellular Biology, who worked on the study with MCB professor Steven Rothstein. “These molecules are non-psychoactive and they target the inflammation at the source, making them ideal painkillers.”
Using a combination of biochemistry and genomics, the researchers were able to determine how cannabis makes two important molecules called cannflavin A and cannflavin B.
Known as “flavonoids,” cannflavins A and B were first identified in 1985, when research verified they provide anti-inflammatory benefits that were nearly 30 times more effective gram-for-gram than acetylsalicylic acid (sold as Aspirin).
However, further investigation into the molecules stalled for decades in part because research on cannabis was highly regulated. With cannabis now legal in Canada and genomics research greatly advanced, Akhtar and Rothstein decided to analyze cannabis in order to understand how Cannabis sativa biosynthesizes cannflavins.
“Our objective was to better understand how these molecules are made, which is a relatively straightforward exercise these days,” said Akhtar. “There are many sequenced genomes that are publicly available, including the genome of Cannabis sativa, which can be mined for information. If you know what you’re looking for, one can bring genes to life, so to speak, and piece together how molecules like cannflavins A and B are assembled.”
With the genomic information at hand, they applied classical biochemistry techniques to verify which cannabis genes were required to create cannflavins A and B. Their full findings were recently published in the journal Phytochemistry.
These findings provide the opportunity to create natural health products containing these important molecules.
“Being able to offer a new pain relief option is exciting, and we are proud that our work has the potential to become a new tool in the pain relief arsenal,” said Rothstein.
Currently, chronic pain sufferers often need to use opioids, which work by blocking the brain’s pain receptors but carry the risk of significant side effects and addiction. Cannflavins would target pain with a different approach, by reducing inflammation.
“The problem with these molecules is they are present in cannabis at such low levels, it’s not feasible to try to engineer the cannabis plant to create more of these substances,” said Rothstein. “We are now working to develop a biological system to create these molecules, which would give us the opportunity to engineer large quantities.”
The research team has partnered with a Toronto-based company, Anahit International Corp., which has licensed a patent from the University of Guelph to biosynthesize cannflavin A and B outside of the cannabis plant.
“Anahit looks forward to working closely with University of Guelph researchers to develop effective and safe anti-inflammatory medicines from cannabis phytochemicals that would provide an alternative to non-steroidal anti-inflammatory drugs,” said Anahit chief operating officer Darren Carrigan.
“Anahit will commercialize the application of cannflavin A and B to be accessible to consumers through a variety of medical and athletic products such as creams, pills, sports drinks, transdermal patches and other innovative options.”
A deceased 67-year-old veteran was given a funeral fit for a king thanks to a compassionate intern and thousands of American neighbors.
According to his obituary, Wayne Lee Wilson passed away on May 28th without any surviving family members. His funerary service was shaping up to be a small memorial ceremony with just 10 of his close friends.
As his service was being orchestrated by Brown Funeral Home and Cremation Service in Nile, Michigan, one of the mortuary’s interns, Drew Mickel, felt compelled to honor the late Vietnam veteran by inviting additional people to the memorial.
Mickel worked with the funeral home and local newspaper in order to publicize the funeral and ask readers to stop by the service on July 17th—and he was stunned by the amount of people who responded.
Quote of the Day: “Recognize that the discomfort or confusion you feel is actually directing you to take charge of your life and make choices that will break you out of stagnation or misery.” – Caroline Myss
Photo: by liz west, CC license
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7-Eleven stores traditionally celebrate July 11th by giving away free slurpees to all of their customers—but one lucky baby is being gifted much more than that.
A Missouri infant named J’Aime Brown is being featured on national news outlets after she was born on July 11th at exactly 7:11PM weighing 7 pounds and 11 ounces.
Her parents, Rachel Langford and Johntez Brown from St. Louis, were so startled by the coincidence, they immediately made plans to tell 7-Eleven staffers about their baby daughter’s serendipitous birth.
One week after company officials learned of J’Aime’s birthday, they told reporters that they would be making a donation to the little girl’s college fund.
“After catching wind of the incredible news, 7-Eleven decided to pledge $7,111 to the newborn’s college fund to honor her entry to the world,” 7-Eleven representatives told USA Today.
“Along with this pledge, the brand has also provided the family with diapers, 7-Eleven onesies, and other newborn goodies to help her parents along the way,” they added.
Representative file photo by Witches Falls Cottages, CC
Taking a hot bath might do much more for your body than just offering you a chance to relax—new research says that it also helps you to get a better night’s sleep.
Systematic review protocols —a method used to search for and analyze relevant data—allowed biomedical engineers at The University of Texas at Austin to analyze thousands of studies linking water-based passive body heating, or bathing and showering with warm/hot water, with improved sleep quality.
To be more exact, researchers in the Cockrell School of Engineering found that bathing 1 to 2 hours before bedtime in water of about 104 to 109 degrees Fahrenheit (40 to 43 degrees Celsius) can significantly improve your sleep.
“When we looked through all known studies, we noticed significant disparities in terms of the approaches and findings,” said Shahab Haghayegh, a Ph.D. candidate in the Department of Biomedical Engineering and lead author on the paper. “The only way to make an accurate determination of whether sleep can in fact be improved was to combine all the past data and look at it through a new lens.”
The paper explaining their method was recently published in the journal Sleep Medicine Reviews.
In collaboration with the UT Health Science Center at Houston and the University of Southern California, the UT researchers reviewed 5,322 studies. They extracted pertinent information from the publications in order to explore the effects of water-based passive body heating on a number of sleep-related conditions: sleep onset latency (the length of time it takes to accomplish the transition from full wakefulness to sleep); total sleep time; sleep efficiency (the amount of time spent asleep relative to the total amount of time spent in bed intended for sleep); and subjective sleep quality.
Meta-analytical tools were then used to assess the consistency between relevant studies and showed that the optimum temperature of 104 to 109 degrees Fahrenheit improved overall sleep quality. When scheduled 1 to 2 hours before bedtime, they also found that bathing can also hasten the speed of falling asleep by an average of 10 minutes.
Much of the science to support links between water-based body heating and improved sleep is already well-established. For example, it is understood that both sleep and our body’s core temperature are regulated by a circadian clock located within the brain’s hypothalamus that drives the 24-hour patterns of many biological processes, including sleep and wakefulness.
Body temperature, which is involved in the regulation of the sleep/wake cycle, exhibits a circadian cycle, being 2 to 3 degrees Fahrenheit higher in the late afternoon/early evening than during sleep, when it is the lowest. The average person’s circadian cycle is characterized by a reduction in core body temperature of about 0.5 to 1º F around an hour before usual sleep time, dropping to its lowest level between the middle and later span of nighttime sleep. It then begins to rise, acting as a kind of a biological alarm clock wake-up signal. The temperature cycle leads the sleep cycle and is an essential factor in achieving rapid sleep onset and high efficiency sleep.
The researchers found the optimal timing of bathing for cooling down of core body temperature in order to improve sleep quality is about 90 minutes before going to bed. Warm baths and showers stimulate the body’s thermoregulatory system, causing a marked increase in the circulation of blood from the internal core of the body to the peripheral sites of the hands and feet, resulting in efficient removal of body heat and decline in body temperature. Therefore, if baths are taken at the right biological time—1 to 2 hours before bedtime—they will aid the natural circadian process and increase one’s chances of not only falling asleep quickly but also of experiencing better quality sleep.
The research team is now working with UT’s Office of Technology Commercialization in the hopes of designing a commercially viable bed system with UT-patented Selective Thermal Stimulation technology. It allows thermoregulatory function to be manipulated on demand and dual temperature zone temperature control that can be tailored to maintain an individual’s optimum temperatures throughout the night.
It all started with a guy on the internet making a satirical Facebook event for people to “storm Area 51” as a means of exposing evidence of alien life to the public—but now, it has become so much more.
The online prankster in question created the social media event earlier this month for the sake of getting a few laughs from his online followers. Since it started to go viral, however, the event has garnered over 3 million interested participants.
Though the joke has resulted in its own fair share of trouble between government officials and social media users, one Oklahoma animal shelter decided to take advantage of the amusing alien meme by asking their followers to “storm their shelter” instead.
The OKC Animal Welfare center in Oklahoma City published a series of photos to Facebook last week depicting several of their resident pups dressed up in their best alien costumes.
“We have great animals ready to protect you from the Area 51 aliens,” wrote the shelter. “Adoption isn’t that far out of this world!”
Within days, the post was shared thousands of times with the hashtag #StormOurShelter.
Dozens of the shelter pups have been adopted in the week following the shelter’s Facebook post. Not only that, internet users have donated over $2,500 to the shelter.
OKC Animal Welfare has not detailed exactly how many of their dogs and cats have been adopted since they started the hashtag, but their Facebook page says that their social media campaign has been a resounding success.
“The response to #StormTheShelter has been out of this world! Thank you all who have supported, shared, donated and adopted,” wrote the shelter.
“Let’s continue to show everyone that adoption isn’t that far out of this world and support your local shelters!”
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It can already be difficult to say a scientific word like “deoxyribonucleotide” let alone spell it out in sign language—but that’s why this determined young university student is being praised for inventing brand new ways for deaf scientists to communicate.
Liam Mcmulkin, who was born deaf, was the first person in his family to pursue a higher education after he enrolled at the University of Dundee to study life sciences in 2015.
Like most first-year students, Mcmulkin had already been anxious about being able to keep up a college workload. Since he was also the only deaf student at the university, he also feared that he would have trouble keeping up with the course lectures.
Though there are some British Sign Language (BSL) translations for scientific vocabulary words, the lexicon becomes fairly limited for college-level communication. As Mcmulkin continued studying in university, he became more and more frustrated by how his translator would be forced to spell out long complex words.
“Watching the interpreters for a one-hour lecture is very tiring,” Mcmulkin told BBC. “There are a lot of new words and scientific words are often very long, like ‘deoxyribonucleotide’ and ‘deoxyribonucleoside’.
“Sometimes the interpreter would be finger spelling for ages and I was having to watch it,” he added. “We would make up new signs which meant it was easier next time, but it also meant I had to learn new signs which was very tiring.”
Photo by University of Dundee
Mcmulkin finally resolved to develop a whole new set of BSL vocabulary words for himself and future life sciences students. To date, he has created over 100 new signs for scientific words that have been officially recognized in formal BSL, which is used by approximately 87,000 people across the UK.
“Liam’s effort towards creating new signs is crucial to the future of the life sciences,” said Dr. Marios Stavridis, Principal Investigator at the School of Life Sciences and supervisor of Mcmulkin’s project. “During his two years of study, he has already developed signs for biology specialist terms ‘on the fly’ and it will be so rewarding to see these terms used in BSL.
“If you imagine having to finger spell highly technical terms whilst sitting in a lecture or having a quick conversation with a colleague, you can appreciate how taxing and difficult it has been for Liam,” he added. “With these signs, Liam and other deaf students will be able to access science on a whole other level.”
As Mcmulkin prepares to study for his master’s degree in September with the goal of eventually becoming a researcher, he is excited to see his new words ease the struggles of other deaf scientists who are following in his footsteps.
(WATCH the interview below)
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